Harmen Reyngoudt

TL;DR: Proton MRS can be used to noninvasively quantify human muscle Carnosine content and muscle carnosine is increased by oral beta-alanine supplementation in sprint-trained athletes; carnosinesine loading slightly but significantly attenuated fatigue in repeated bouts of exhaustive dynamic contractions; and the increase in muscle Carnival did not improve isometric endurance or 400-m race time.

TL;DR: It can be concluded that carnosine is a stable compound in human skeletal muscle, confirming the absence of carnosinase in myocytes, and shows that washout periods for crossover designs in supplementation studies for muscle metabolites may sometimes require months rather than weeks.

TL;DR: The altered metabolic concentrations indicate that the energy metabolism in MwoA patients is impaired, certainly in a subgroup of patients, and adds further strength to the theory of the presence of a mitochondrial component in the pathophysiology of migraine.

TL;DR: Differences between water and fat T1 and T2 relaxivities are exploited by applying a bi‐component extended phase graph (EPG) fitting approach to simultaneously quantify the muscle water T2 and fat fraction from standard multi‐slice multi‐echo (MSME) acquisitions in the presence of stimulated echoes.

TL;DR: In this paper, Proton magnetic resonance spectroscopy (1H-MRS) was performed in the posterior cingulate cortex (PCC) and the left hippocampus (HC) of 90 healthy subjects.