H
Harold D. Frankl
Researcher at Kaiser Permanente
Publications - 38
Citations - 3434
Harold D. Frankl is an academic researcher from Kaiser Permanente. The author has contributed to research in topics: Odds ratio & Colorectal adenoma. The author has an hindex of 27, co-authored 38 publications receiving 3388 citations.
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Journal ArticleDOI
A Clinical Trial of Antioxidant Vitamins to Prevent Colorectal Adenoma
E. Robert Greenberg,John A. Baron,Tor D. Tosteson,Daniel H. Freeman,Gerald J. Beck,John H. Bond,Thomas A. Colacchio,John A. Coller,Harold D. Frankl,Robert W. Haile,Jack S. Mandel,David W. Nierenberg,Richard I. Rothstein,Dale C. Snover,Marguerite Stevens,Robert W. Summers,Rosalind U. van Stolk +16 more
TL;DR: The lack of efficacy of these vitamins argues against the use of supplemental beta carotene and vitamins C and E to prevent colorectal cancer.
Journal ArticleDOI
The Relation of Gastroesophageal Reflux Disease and Its Treatment to Adenocarcinomas of the Esophagus and Gastric Cardia
Wong-Ho Chow,William D. Finkle,Joseph K. McLaughlin,Harold D. Frankl,Harry K. Ziel,Joseph F. Fraumeni +5 more
TL;DR: Findings provide reassuring findings that use of H 2 antagonists and anticholinergics does not increase AEC risk and quantifies the elevated risk of AEC associated with gastroesophageal reflux disease.
Journal Article
Glutathione transferase null genotype, broccoli, and lower prevalence of colorectal adenomas.
Henry J. Lin,Nicole Probst-Hensch,Andrew D. Louie,Irving H Kau,John S. Witte,Sue A. Ingles,Harold D. Frankl,Eric R. Lee,Robert W. Haile +8 more
TL;DR: The observed broccoli-GSTM1 interaction is compatible with an isothiocyanate mechanism, and a protective effect of broccoli was observed only among subjects with the GSTM1 null genotype.
Journal ArticleDOI
The relation of gastroesophageal reflux disease and its treatment to adenocarcinomas of the esophagus and gastric cardia
Wong-Ho Chow,William D. Finkle,Joseph K. McLaughlin,Harold D. Frankl,Harry K. Ziel,Joseph F. Fraumeni +5 more
TL;DR: This study provides reassuring findings that use of H2 antagonists and anticholinergics does not increase AEC risk and quantifies the elevated risk of AEC associated with gastroesophageal reflux disease.
Journal ArticleDOI
Relation of Vegetable, Fruit, and Grain Consumption to Colorectal Adenomatous Polyps
John S. Witte,Matthew P. Longnecker,Cristy L. Bird,Eric R. Lee,Harold D. Frankl,Robert W. Haile +5 more
TL;DR: Findings support the hypothesis that high intake of vegetables, fruits, or grains decreases the risk of polyps and suggest that any protective effects might reflect unmeasured constituents in these foods.