H
Haroldo Cesar de Oliveira
Researcher at Oswaldo Cruz Foundation
Publications - 56
Citations - 1799
Haroldo Cesar de Oliveira is an academic researcher from Oswaldo Cruz Foundation. The author has contributed to research in topics: Paracoccidioides brasiliensis & Paracoccidioides. The author has an hindex of 19, co-authored 51 publications receiving 1193 citations. Previous affiliations of Haroldo Cesar de Oliveira include Sao Paulo State University & Carlos III Health Institute.
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The Fungal Cell Wall: Candida, Cryptococcus, and Aspergillus Species.
TL;DR: Recent data on the composition and synthesis, influence of the components of the cell wall in fungi-host interaction and the role as a target for the next generation of antifungal drugs in yeasts and filamentous fungi are reviewed.
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Antifungal Therapy: New Advances in the Understanding and Treatment of Mycosis.
Liliana Scorzoni,Ana Elizabete Silva,Caroline Maria Marcos,Patricia Akemi Assato,Wanessa C.M.A. de Melo,Haroldo Cesar de Oliveira,Caroline Barcelos Costa-Orlandi,Maria José Soares Mendes-Giannini,Ana Marisa Fusco-Almeida +8 more
TL;DR: Different approaches to preventing and treating fungal diseases are described in this review, with a focus on the resistance mechanisms of fungi, with the goal of developing efficient strategies to overcoming and preventing resistance as well as new advances in antifungal therapy.
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Fungal Biofilms and Polymicrobial Diseases
Caroline Barcelos Costa-Orlandi,Janaina de Cássia Orlandi Sardi,Nayla de Souza Pitangui,Haroldo Cesar de Oliveira,Liliana Scorzoni,Mariana Cristina Galeane,Kaila P. Medina-Alarcón,Wanessa C.M.A. de Melo,Monica Yonashiro Marcelino,Jaqueline Derissi Braz,Ana Marisa Fusco-Almeida,Maria José Soares Mendes-Giannini +11 more
TL;DR: Several in vitro techniques have been developed to study fungal biofilms, from colorimetric methods to omics approaches that aim to identify new therapeutic strategies by developing new compounds to combat these microbial communities as well as new diagnostic tools to identify these complex formations in vivo.
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Cryptococcus neoformans can form titan-like cells in vitro in response to multiple signals
Nuria Trevijano-Contador,Haroldo Cesar de Oliveira,Haroldo Cesar de Oliveira,Rocío García-Rodas,Suélen Andreia Rossi,Irene Llorente,Ángel Zaballos,Guilhem Janbon,Joaquín Ariño,Oscar Zaragoza +9 more
TL;DR: In vitro conditions (low nutrient, serum supplemented medium at neutral pH) that promote the transition from regular to titan-like cells are described, providing a new alternative method to investigate titan cell formation devoid the bioethical problems that involve animal experimentation.
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Paracoccidoides brasiliensis 30 kDa adhesin: identification as a 14-3-3 protein, cloning and subcellular localization in infection models.
Julhiany de Fátima da Silva,Haroldo Cesar de Oliveira,Caroline Maria Marcos,Rosângela Aparecida Moraes da Silva,Tania Alves da Costa,Vera Lúcia Garcia Calich,Ana Marisa Fusco Almeida,Maria José Soares Mendes-Giannini +7 more
TL;DR: Cloned, expressed, and determined the role of the 14-3-3 protein in a heterologous system and its subcellular localization in in vitro and in vivo infection models to lead to a better understanding of P. brasiliensis interactions with host tissues and paracoccidioidomycosis pathogenesis.