H
Harvey T. McMahon
Researcher at Laboratory of Molecular Biology
Publications - 130
Citations - 33027
Harvey T. McMahon is an academic researcher from Laboratory of Molecular Biology. The author has contributed to research in topics: Endocytosis & Clathrin. The author has an hindex of 77, co-authored 126 publications receiving 30231 citations. Previous affiliations of Harvey T. McMahon include University of Cambridge & Medical Research Council.
Papers
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Mechanisms of Endocytosis
TL;DR: What is known about mammalian endocytic mechanisms is reviewed, with focus on the cellular proteins that control these events, and the functional relevance of distinctendocytic pathways is discussed.
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Membrane curvature and mechanisms of dynamic cell membrane remodelling
TL;DR: Membrane curvature is no longer seen as a passive consequence of cellular activity but an active means to create membrane domains and to organize centres for membrane trafficking.
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Molecular mechanism and physiological functions of clathrin-mediated endocytosis
TL;DR: Clathrin-mediated endocytosis is the endocytic portal into cells through which cargo is packaged into vesicles with the aid of a clathrin coat and is fundamental to neurotransmission, signal transduction and the regulation of many plasma membrane activities and is thus essential to higher eukaryotic life.
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BAR domains as sensors of membrane curvature: the amphiphysin BAR structure
Brian J. Peter,Helen M. Kent,Ian G. Mills,T. Yvonne Vallis,P. Jonathan G. Butler,Philip R. Evans,Harvey T. McMahon +6 more
TL;DR: The structure of the Drosophila amphiphysin BAR domain is solved and it is predicted that BAR domains are in many protein families, including sorting nexins, centaurins, and oligophrenins.
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The dynamin superfamily: universal membrane tubulation and fission molecules?
TL;DR: It is proposed that a common mechanism leading to membrane tubulation and/or fission could encompass their many varied functions.