H
Hasso Scholz
Researcher at University of Hamburg
Publications - 135
Citations - 7031
Hasso Scholz is an academic researcher from University of Hamburg. The author has contributed to research in topics: Isoprenaline & Adenosine. The author has an hindex of 46, co-authored 135 publications receiving 6847 citations. Previous affiliations of Hasso Scholz include University of Tennessee Health Science Center & Hannover Medical School.
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Journal ArticleDOI
Three-dimensional reconstitution of embryonic cardiomyocytes in a collagen matrix: a new heart muscle model system.
Thomas Eschenhagen,Christine Fink,Ute Remmers,Hasso Scholz,Jens Wattchow,Joachim Weil,Wolfram H. Zimmermann,Hans H. Dohmen,Hansjörg Schäfer,Nanette H. Bishopric,Tetsuro Wakatsuki,Elliot L. Elson +11 more
TL;DR: The utility of this system as a test bed for genetic manipulation was demonstrated by infecting the CMPMs with a recombinant β‐galactosidase‐carrying adenovirus, and transduction efficiency increased from about 5% (MOI 0.1) to about 50% ( MOI 100).
Journal ArticleDOI
Increase in myocardial Gi-proteins in heart failure.
TL;DR: It is conceivable that an increase in myocardial Gi-proteins is causally related to heart failure due to idiopathic dilated cardiomyopathy, and in the preparation from the patient with inflammatory heart disease the contractile response to isoprenaline was not reduced and likewise content of Gi- Proteins was not changed.
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Increased expression of cardiac phosphatases in patients with end-stage heart failure
Joachim Neumann,Thomas Eschenhagen,Larry R. Jones,Bettina Linck,Wilhelm Schmitz,Hasso Scholz,Norbert Zimmermann +6 more
TL;DR: Enhanced activity of phosphatases may be causally related to heart failure and/or may aggravate the well known decreased cardiac responsiveness to positive inotropic agents in end-stage heart failure.
Journal ArticleDOI
Activity of cAMP-dependent protein kinase and Ca2+/calmodulin-dependent protein kinase in failing and nonfailing human hearts
TL;DR: Increased CaM kinase activity in hearts from patients with dilated cardiomyopathy could play a role in the abnormal Ca2+ handling of the SR and heart muscle cell.
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Increased messenger RNA level of the inhibitory G protein alpha subunit Gi alpha-2 in human end-stage heart failure.
Thomas Eschenhagen,Ulrike Mende,Monika Nose,Wilhelm Schmitz,Hasso Scholz,A Haverich,S Hirt,Volker Döring,Peter Kalmár,W Höppner +9 more
TL;DR: Gi alpha-2 and Gi alpha-3 mRNA are the predominant Gi alpha mRNA subtypes in human ventricular myocardium as in other mammalian species.