Heather Bentley

TL;DR: Objective, laboratory based functional measures, such as those used here, may compliment NP testing in future studies directed at understanding the impact on life quality of central nervous system disorders and their treatments.

TL;DR: Smoked cannabis was generally well tolerated and effective when added to concomitant analgesic therapy in patients with medically refractory pain due to HIV DSPN.

TL;DR: This study adds to a growing body of evidence that cannabis may be effective at ameliorating neuropathic pain, and may be an alternative for patients who do not respond to, or cannot tolerate, other drugs, however, the use of marijuana as medicine may be limited by its method of administration and modest acute cognitive effects, particularly at higher doses.

TL;DR: There is a window of modest analgesia for smoked cannabis, with lower doses decreasing pain and higher doses increasing pain, this study suggests.

TL;DR: Smoked cannabis was superior to placebo in symptom and pain reduction in participants with treatment-resistant spasticity, and future studies should examine whether different doses can result in similar beneficial effects with less cognitive impact.