Showing papers in "The Journal of Pain in 2008"

TL;DR: A consensus meeting was convened by the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT) to provide recommendations for interpreting clinical importance of treatment outcomes in clinical trials of the efficacy and effectiveness of chronic pain treatments as discussed by the authors.

TL;DR: It is concluded that common pain conditions affect a large percentage of persons in both developed and developing countries, and the prevalence of pain is greater among females and among older persons.

TL;DR: Based on systematic review and consensus of experts, core domains and measures for clinical trials to treat pain in children and adolescents were defined to assist in comparison and pooling of data and promote evidence-based treatment.

TL;DR: It is shown that chronic pain is a highly prevalent condition in the community, one that can exert negative consequence for the child, but the prevalence of severe chronic pain cases is low and a new grading system of chronic pediatric problems is suggested.

TL;DR: A psychophysiological systems view of pain in which physical injury, or wounding, generates a complex stress response that extends beyond the nervous system and contributes to the experience of pain is advanced.

TL;DR: The obtained psychometrics suggest that the SOAPP-R is an improvement over the original version in screening risk potential for aberrant medication-related behavior among persons with chronic pain, and is less susceptible to overt deception than the original SOAPP version 1.

TL;DR: Nabilone appears to be a beneficial, well-tolerated treatment option for fibromyalgia patients, with significant benefits in pain relief and functional improvement, in the first randomized, double-blind, placebo-controlled trial of its kind.

TL;DR: This study adds to a growing body of evidence that cannabis may be effective at ameliorating neuropathic pain, and may be an alternative for patients who do not respond to, or cannot tolerate, other drugs, however, the use of marijuana as medicine may be limited by its method of administration and modest acute cognitive effects, particularly at higher doses.

TL;DR: This randomized, placebo-controlled trial of 300, 450, and 600 mg/d of pregabalin monotherapy demonstrated that all 3 doses were efficacious for up to 14 weeks for the treatment of fibromyalgia and were well tolerated by most patients.

TL;DR: Strong correlations emerged between different reporters of school functioning indicators such as attendance, suggesting that reliance on parent or adolescent reporting may be sufficient when assessing these domains and the importance of broadly assessing school functioning in adolescents with chronic pain.

TL;DR: Satisfaction with social support is significantly associated with a depressed mood and pain intensity, but not with functional disability, and perceived social support and pain coping are independent predictors of chronic pain adjustment, providing support for a biopsychosocial model of pain.

TL;DR: Several themes were identified related to pain reduction, improved attention, improved sleep, and achieving well-being resulting from mindfulness meditation that suggest it has promising potential as a nonpharmacologic treatment of chronic pain for older adults.

TL;DR: Deep inhibition of ovarian sex hormone and adrenal androgen production among women chronically consuming sustained-action opioids is demonstrated, demonstrating profound inhibition of menstrual flow and possible contributions to opioid-associated depression, osteoporosis, and hyperalgesia.

TL;DR: Findings indicate that the addition of naloxone to oxycodone in a PR combination tablet offers improved tolerability, and may improve the acceptability of long-term opioid treatment for chronic pain.

TL;DR: In this article, the authors investigated the prevalence of the neuropathic component in chronic pain after thoracic surgery, and looked for predictive factors for prevalence and intensity of chronic pain.

TL;DR: Overall, the use of dronabinol was found to result in additional analgesia among patients taking opioids for chronic noncancer pain, and the results of the preliminary study suggest that dRONabinol, a synthetic THC, may have an additive effect on pain relief.

TL;DR: Results suggest that it is the activation magnitude of SI, which solely establishes the significant correlation with subjective pain ratings, in accordance with the classical clinical thinking, relating SI lesions to diminished perception of pain.

TL;DR: It is suggested that oxaliplatin acts on IB4 (+)-nociceptors to induce oxidative stress-dependent acute peripheral sensory neuropathy, and this information could help define cellular targets against which protective therapies could be developed.

TL;DR: Comprehensive assessments of pain are necessary for clinical research on the epidemiology, natural history, pathophysiologic mechanisms, treatment, and prevention of pain in herpes zoster and PHN.

TL;DR: The findings of this study and others suggest that persons with FM display sensitivity to a number of sensory stimuli, and suggest that FM is associated with a global central nervous system augmentation of sensory information.

TL;DR: Although pain-related fear has received less attention in the experimental literature than pain catastrophizing, results of the current study are consistent with clinical reports highlighting this variable as an important aspect of the experience of pain.

TL;DR: The results suggest that TRPV1 may be essential for heat transduction in a specific subset of mechanically insensitive cutaneous nociceptors and that this subset may constitute a discrete heat input pathway for inflammation-induced thermal pain.

TL;DR: More than one-third of the women who separated from their abusive partners on average 20 months previously experienced high disability pain as measured by Von Korff's chronic pain grade as mentioned in this paper, which was associated with visits to a family doctor and psychiatrist and use of medication in more than prescribed dosages.

TL;DR: In this paper, a critical review of the psychometric properties of 6 objective pain measures that were developed to assess pain in nonverbal adult patients in the ICU is provided, as well as their applicability for use with this patient population.

TL;DR: In unadjusted logistic regression analyses, the presence of any pain condition was associated with lifetime and 12-month suicidal ideation, plan, and attempt, and among pain subtypes, severe or frequent headaches and "other" chronic pain remained significantly associated with Lifetime suicidal Ideation and plan.

TL;DR: In this article, the authors examined the time to onset of pain relief and improvement in allodynia in 269 patients with postherpetic neuralgia in a 4-week randomized trial.

TL;DR: The findings suggest that socioeconomic distress defined at both the individual level and at the neighborhood/community level are significant independent predictors of pain-related disability and HRQOL in children with SCD.

TL;DR: A significant correlation was found between the forearm and the leg for both psychophysics and EPs amplitude and regression analysis revealed pain perception and not stimulus intensity as the major contributing factor.

TL;DR: The effect of ALND on the prevalence and intensity of chronic pain after breast cancer surgery and the quality of life in patients was mainly affected by chronic pain and to a lesser extent by type of surgery.

TL;DR: Preliminary evidence is found for the importance of parent characteristics, beyond situational characteristics, in parental emotional responses to their child's pain, within recent models of empathy and pain.