H
Heesang Song
Researcher at Yonsei University
Publications - 33
Citations - 1266
Heesang Song is an academic researcher from Yonsei University. The author has contributed to research in topics: Mesenchymal stem cell & Apoptosis. The author has an hindex of 18, co-authored 28 publications receiving 1192 citations. Previous affiliations of Heesang Song include Chosun University & Washington University in St. Louis.
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Journal ArticleDOI
Reactive oxygen species inhibit adhesion of mesenchymal stem cells implanted into ischemic myocardium via interference of focal adhesion complex.
Heesang Song,Min Ji Cha,Byeong-Wook Song,Il-Kwon Kim,Woochul Chang,Soyeon Lim,Eun-Ju Choi,Onju Ham,Se-Yeon Lee,Namsik Chung,Yangsoo Jang,Ki-Chul Hwang +11 more
TL;DR: Investigation of the role of ROS on MSC adhesion indicates that ROS inhibit cellular adhesion of engrafted MSCs and provides evidence that the elimination of ROS might be a novel strategy for improving the survival ofEngrafted M SCs.
Journal Article
Transfection of mesenchymal stem cells with the FGF-2 gene improves their survival under hypoxic conditions
Heesang Song,Kihwan Kwon,Soyeon Lim,Seok Min Kang,Young Guk Ko,Zheng Zhe Xu,Ji Hyung Chung,Byung Soo Kim,Hakbae Lee,Boyoung Joung,Sungha Park,Donghoon Choi,Yangsoo Jang,Namsik Chung,Kyung-Jong Yoo,Ki-Chul Hwang +15 more
TL;DR: The data suggest that genetic modification of MSCs before transplantation could be useful for treating myocardial infarction and end-stage cardiac failure.
Journal ArticleDOI
Modification of mesenchymal stem cells for cardiac regeneration
TL;DR: Modification of MSCs before transplantation has developed into a promising option for enhancing the beneficial effects of M SC-based therapy for cardiac repair after myocardial infarction.
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Tissue Transglutaminase Is Essential for Integrin-Mediated Survival of Bone Marrow-Derived Mesenchymal Stem Cells
Heesang Song,Woochul Chang,Soyeon Lim,Hye-Sun Seo,Chi Young Shim,Sungha Park,Kyung-Jong Yoo,Byung-Soo Kim,Byoung-Hyun Min,Hakbae Lee,Yangsoo Jang,Namsik Chung,Ki-Chul Hwang +12 more
TL;DR: It is suggested that tTG may play an important role in integrin‐mediated adhesion of MSCs in implanted tissues.
Journal ArticleDOI
Mesenchymal stem cells pretreated with delivered Hph-1-Hsp70 protein are protected from hypoxia-mediated cell death and rescue heart functions from myocardial injury.
Woochul Chang,Byeong-Wook Song,Soyeon Lim,Heesang Song,Chi Young Shim,Min-Ji Cha,Dong Hyuck Ahn,Young-Gook Jung,Dong Ho Lee,Ji Hyung Chung,Ki-Doo Choi,Seung-Kyou Lee,Namsik Chung,Sang Kyou Lee,Yangsoo Jang,Ki-Chul Hwang +15 more
TL;DR: In this paper, the authors directly delivered Hsp70, a protein with protective functions against stress, into mesenchymal stem cells (MSC) for myocardial injury.