H
Heeyeong Cho
Researcher at Korea University of Science and Technology
Publications - 40
Citations - 676
Heeyeong Cho is an academic researcher from Korea University of Science and Technology. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 12, co-authored 34 publications receiving 567 citations. Previous affiliations of Heeyeong Cho include Samsung.
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Journal ArticleDOI
Modulation of the activity of pro-inflammatory enzymes, COX-2 and iNOS, by chrysin derivatives
Heeyeong Cho,Cheol Won Yun,Woo Kyu Park,Jae Yang Kong,Kyoung Soon Kim,Youmie Park,Sang-Hyun Lee,Bak Kwang Kim +7 more
TL;DR: Evidence is presented that several chrysin derivatives modulate the activities, as well as the expression, of COX-2 and iNOS enzymes, and that a hydrogen bond exists between the oxygen of the ketone group at the 7-position of Ch-4 and the hydroxyl group of Tyr355.
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Fucoidan from Undaria pinnatifida induces apoptosis in A549 human lung carcinoma cells.
Hye-Jin Boo,Jae-Hee Hyun,Sang-Cheol Kim,Jung-Il Kang,Min-Kyoung Kim,Sun Yeou Kim,Heeyeong Cho,Eun-Sook Yoo,Hee-Kyoung Kang +8 more
TL;DR: Results indicate that fucoidan induces apoptosis of A549 human lung cancer cells through down‐regulation of p38, PI3K/Akt, and the activation of the ERK1/2 MAPK pathway.
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Biological evaluation of tanshindiols as EZH2 histone methyltransferase inhibitors.
Jimin Woo,Hyun Young Kim,Byung Jin Byun,Chonghak Chae,Ji Young Lee,Shi Yong Ryu,Woo-Kyu Park,Heeyeong Cho,Gildon Choi +8 more
TL;DR: The findings strongly suggest that tanshindiols possess a unique anti-cancer activity whose mechanism involves the inhibition of EZH2 activity and would provide chemically valuable information for designing a new class of potent EZh2 inhibitors.
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KKHA-761, a potent D3 receptor antagonist with high 5-HT1A receptor affinity, exhibits antipsychotic properties in animal models of schizophrenia.
Woo-Kyu Park,Daeyoung Jeong,Heeyeong Cho,Seong Jin Lee,Mi Young Cha,Ae Nim Pae,Kyung Il Choi,Hun Yeong Koh,Jae Yang Kong +8 more
TL;DR: It is suggested that KKHA-761 is a potent antipsychotic agent with combined dopamine D3 and serotonin 5-HT1A receptors modulation activity, which may further enhance its therapeutic potential for anxiety, psychotic depression, and other related disorders.
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Inhibition of c-Kit signaling by diosmetin isolated from Chrysanthemum morifolium
Seong Jin Lee,Tae-Hoon Jung,Hojeong Kim,Daeyoung Jeong,Gildon Choi,Woo-Kyu Park,Jae Yang Kong,Mu-Hyun Jin,Heeyeong Cho +8 more
TL;DR: Results strongly suggest that C. morifolium extract and diosmetin have potential to suppress SCF-/UVB-induced melanogenesis, and could be developed as anti-pigmentation agents.