H
Heidi B. Kaplan
Researcher at University of Texas Health Science Center at Houston
Publications - 52
Citations - 6507
Heidi B. Kaplan is an academic researcher from University of Texas Health Science Center at Houston. The author has contributed to research in topics: Myxococcus xanthus & Gene. The author has an hindex of 27, co-authored 50 publications receiving 5848 citations. Previous affiliations of Heidi B. Kaplan include Dartmouth College & Stanford University.
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Journal ArticleDOI
Suppressors that permit A-signal-independent developmental gene expression in Myxococcus xanthus.
TL;DR: To identify links between A signal and its responsive gene, omega 4521, suppressors of an asg mutation were generated and implicate the sasA+ product as a negative regulator in the A-signal-dependent regulation of omega4521.
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The Myxococcus xanthus rfbABC operon encodes an ATP-binding cassette transporter homolog required for O-antigen biosynthesis and multicellular development.
TL;DR: Data indicate that the sasA locus is required for the biosynthesis of O-antigen and, when mutated, results in A-signal-independent expression of 4521, which is critical for Myxococcus xanthus multicellular development.
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Multicellular development and gliding motility in Myxococcus xanthus.
TL;DR: A great deal of progress has been made in the studies of fruiting body development and social gliding in Myxocococcus xanthus in the past few years, including identification of the bone fide C-signal and a receptor for type IV pili, and development of a model for the mechanism of adventurous gliding motility.
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Myxococcus xanthus gliding motors are elastically coupled to the substrate as predicted by the focal adhesion model of gliding motility.
Rajesh Balagam,Douglas B. Litwin,Fabian Czerwinski,Mingzhai Sun,Heidi B. Kaplan,Joshua W. Shaevitz,Oleg A. Igoshin +6 more
TL;DR: Using a biophysical model of the M. xanthus cell, evidence is found for elastic coupling in support of the focal adhesion model and comparison of modeling results with experimental data for cell-cell collision events pointed to a strong, elastic attachment.
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Characterization of a Myxococcus xanthus mutant that is defective for adventurous motility and social motility
Hope Lancero,Nora B. Caberoy,Schryl Castaneda,Yinuo Li,Ann Lu,David Dutton,Xue Yan Duan,Heidi B. Kaplan,Wenyuan Shi,Anthony G. Garza +9 more
TL;DR: It is proposed that the putative transcriptional activator Nla24 regulates a subset of genes that are important for A-Motility and S-motility in M. xanthus.