A
Adam Kuspa
Researcher at Baylor College of Medicine
Publications - 103
Citations - 7667
Adam Kuspa is an academic researcher from Baylor College of Medicine. The author has contributed to research in topics: Dictyostelium discoideum & Dictyostelium. The author has an hindex of 45, co-authored 103 publications receiving 7371 citations. Previous affiliations of Adam Kuspa include Stanford University & Rice University.
Papers
More filters
Journal ArticleDOI
The genome of the social amoeba Dictyostelium discoideum
Ludwig Eichinger,Justin A. Pachebat,Justin A. Pachebat,Gernot Glöckner,Marie-Adèle Rajandream,Richard Sucgang,Matthew Berriman,J. Song,Rolf Olsen,Karol Szafranski,Qikai Xu,Budi Tunggal,Sarah K. Kummerfeld,Martin Madera,Bernard Anri Konfortov,Francisco Rivero,Alan T. Bankier,Rüdiger Lehmann,N. Hamlin,Robert L. Davies,Pascale Gaudet,Petra Fey,Karen E Pilcher,Guokai Chen,David L. Saunders,Erica Sodergren,P. Davis,Arnaud Kerhornou,X. Nie,Neil Hall,Christophe Anjard,Lisa Hemphill,Nathalie Bason,Patrick Farbrother,Brian A. Desany,Eric M. Just,Takahiro Morio,René Rost,Carol Churcher,J. Cooper,Stephen F. Haydock,N. van Driessche,Ann Cronin,Ian Goodhead,Donna M. Muzny,T. Mourier,Arnab Pain,Mingyang Lu,D. Harper,R. Lindsay,Heidi Hauser,Kylie R. James,M. Quiles,M. Madan Babu,Tsuneyuki Saito,Carmen Buchrieser,A. Wardroper,A. Wardroper,Marius Felder,M. Thangavelu,D. Johnson,Andrew J Knights,H. Loulseged,Karen Mungall,Karen Oliver,Claire Price,Michael A. Quail,Hideko Urushihara,Judith Hernandez,Ester Rabbinowitsch,David Steffen,Mandy Sanders,Jun Ma,Yuji Kohara,Sarah Sharp,Mark Simmonds,S. Spiegler,Adrian Tivey,Sumio Sugano,Brian White,Danielle Walker,John Woodward,Thomas Winckler,Yoshiaki Tanaka,Gad Shaulsky,Michael Schleicher,George M. Weinstock,André Rosenthal,Edward C. Cox,Rex L. Chisholm,Richard A. Gibbs,William F. Loomis,Matthias Platzer,Robert R. Kay,Jeffrey G. Williams,Paul H. Dear,Angelika A. Noegel,Bart Barrell,Adam Kuspa +98 more
TL;DR: A proteome-based phylogeny shows that the amoebozoa diverged from the animal–fungal lineage after the plant–animal split, but Dictyostelium seems to have retained more of the diversity of the ancestral genome than have plants, animals or fungi.
Journal ArticleDOI
Tagging developmental genes in Dictyostelium by restriction enzyme-mediated integration of plasmid DNA.
Adam Kuspa,William F. Loomis +1 more
TL;DR: Electroporating BamHI or EcoRI together with pyr5-6 plasmids cut with the same enzyme stimulates the efficiency of transformation in Dictyostelium discoideum more than 20-fold over the rate seen when plasmid DNA alone is introduced.
Journal ArticleDOI
A global analysis of developmentally regulated genes in Myxococcus xanthus
Lee Kroos,Adam Kuspa,Dale Kaiser +2 more
TL;DR: The developmentally regulated Tn5 lac insertions described here provide a set of at least 29 new developmental markers for Myxococcus.
Journal ArticleDOI
Sequence and analysis of chromosome 2 of Dictyostelium discoideum
Gernot Glöckner,Ludwig Eichinger,Karol Szafranski,Justin A. Pachebat,Alan T. Bankier,Paul H. Dear,Rüdiger Lehmann,Cornelia Baumgart,Genís Parra,Josep F. Abril,Roderic Guigó,Kai Kumpf,Budi Tunggal,Edward C. Cox,Michael A. Quail,Matthias Platzer,André Rosenthal,Angelika A. Noegel,Bart Barrell,Marie-Adèle Rajandream,Jeffrey G. Williams,Robert R. Kay,Adam Kuspa,Richard A. Gibbs,Richard Sucgang,Donna M. Muzny,Brian A. Desany,Kathy Zeng,Baoli Zhu,Pieter J. de Jong,Theodor Dingermann,Günther Gerisch,Peter Philippsen,Michael Schleicher,Stephan C. Schuster,Thomas Winckler +35 more
TL;DR: A significant number of the genes show higher similarities to genes of vertebrates than to those of other fully sequenced eukaryotes, which strengthens the view that the evolutionary position of D. discoideum is located before the branching of metazoa and fungi but after the divergence of the plant kingdom.
Journal ArticleDOI
Immune-like phagocyte activity in the social amoeba.
TL;DR: An apparent innate immune function in social amoebae, and the use of TirA for bacterial feeding, suggest an ancient cellular foraging mechanism that may have been adapted to defense functions well before the diversification of the animals.