H
Heike Engel
Researcher at University of Texas MD Anderson Cancer Center
Publications - 10
Citations - 1069
Heike Engel is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Leukemia & Bone marrow. The author has an hindex of 8, co-authored 10 publications receiving 1059 citations.
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Journal ArticleDOI
Allogeneic Blood Stem Cell Transplantation for Refractory Leukemia and Lymphoma: Potential Advantage of Blood Over Marrow Allografts
Martin Korbling,Donna Przepiorka,Yang O. Huh,Heike Engel,K. Van Besien,Sergio Giralt,Borje S. Andersson,Hans Dieter Kleine,D. Seong,Albert B. Deisseroth +9 more
TL;DR: Cryopreserved, filgrastim-stimulated allogeneic PBSCs may be a suitable alternative to allogenic marrow for transplantation with the advantage of more rapid platelet recovery, and further studies are required to assess long-term risks of chronic GVHD.
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Allogeneic blood stem cell transplantation: peripheralization and yield of donor-derived primitive hematopoietic progenitor cells (CD34+ Thy-1dim) and lymphoid subsets, and possible predictors of engraftment and graft-versus-host disease.
Martin Korbling,Yang O. Huh,A. Durett,Nadeem Q. Mirza,P. Miller,Heike Engel,Paolo Anderlini,K. Van Besien,Michael Andreeff,Donna Przepiorka,Albert B. Deisseroth,Richard E. Champlin +11 more
TL;DR: Forty-one normal donors were studied to assess the effects of recombinant human granulocyte colony-stimulating factor (rhG-CSF) on the peripheralization of hematopoietic progenitor cells and lymphoid subsets and the actuarial probability of developing acute GVHD.
Journal Article
Retinoic Acid-induced Expression of CD38 Antigen in Myeloid Cells Is Mediated through Retinoic Acid Receptor-α
Johannes Drach,Teresa McQueen,Heike Engel,Michael Andreeff,Kent A. Robertson,Steven J. Collins,Fabio Malavasi,Kapil Mehta +7 more
TL;DR: It is concluded that CD38 is ATRA inducible in myeloid leukemia cells and normal CD34 + bone marrow cells, suggesting a similar role for RARα in CD38 expression in other hematopoietic cells.
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Quantitation of minimal residual disease in acute myelogenous leukemia and myelodysplastic syndromes in complete remission by molecular cytogenetics of progenitor cells
Heike Engel,Johannes Drach,Afsaneh Keyhani,Shuwei Jiang,Nguyen T. Van,Marek Kimmel,Gisela Sanchez-Williams,Angela Goodacre,M. Andreeff +8 more
TL;DR: Cox regression analysis showed that cytogenetic class and levels of clonal cells at CR were related to time to relapse and the level of MRD identified patients at high and low risk of relapse.
Journal Article
Large-scale preparation of highly purified, frozen/thawed CD34+, HLA-DR- hematopoietic progenitor cells by sequential immunoadsorption (CEPRATE SC) and fluorescence-activated cell sorting: implications for gene transduction and/or transplantation.
M. Korbling,Johannes Drach,Richard E. Champlin,Heike Engel,L. Huynh,Hans Dieter Kleine,R. Berenson,Albert B. Deisseroth,Michael Andreeff +8 more
TL;DR: One million highly purified CD34+, DR- progenitor cells is potentially an adequate cell dose for autologous transplantation equivalent to what is contained in an unselected and functioning marrow autograft.