Heike Münzberg

TL;DR: The data suggest that either BCAAs do not act as physiological signals of protein status or the loss of BCAA metabolism within brain glia impairs the detection of protein balance.

TL;DR: The neural activation pattern and dynamics suggest a role of the brainstem anorexia pathway in the early effects of RYGB on meal size and food intake that may lead to adaptive neural and behavioral changes involved in the control of food intake and body weight at a lower level.

TL;DR: It is concluded that bile acid signaling through TGR5 is not required for the beneficial effects of RY GB in the mouse and that RYGB and VSG may achieve their similar beneficial effects through different mechanisms.

TL;DR: To test the commonly held assumption that gastric bypass surgery lowers body weight because it limits the ability to eat large amounts of food, a large amount of food is eaten in order to test the assumption.

TL;DR: FGF21 signaling is not a critical single factor for the beneficial metabolic effects of RYGB, which may open up the possibility to use FGF21 as adjuvant therapy in patients with ineffective bariatric surgeries.