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Showing papers by "Helen Christensen published in 1995"


Journal ArticleDOI
TL;DR: It is confirmed in a population sample that the epsilon 4 allele is a risk factor for dementia, but the suggestion that homozygosity for the ePSilon 4 alleles is sufficient for the development of Alzheimer's disease is refuted.

274 citations


Journal ArticleDOI
TL;DR: It was concluded that the wish to die is associated with several factors in addition to depression and may be present in individuals with few depressive symptoms, and there is a need to investigate whether factors associated with the wishing to die are treatable and whether this can restore the desire to live.
Abstract: This study aimed to determine the prevalence of the wish to die in elderly people and investigate the factors associated with it, in particular, whether factors other than depression contribute to the wish to die. Data were obtained from an Australian epidemiological survey of people aged 70 or more. Survey participants were asked whether, in the last two weeks, they had felt that they wanted to die and, if so, if they had had such thoughts repeatedly. Three classes of possible risk factors were investigated: sociodemographic factors (age, sex, marital status), mental health (depression, cognitive impairment), and physical health (poor self-rated health, disability, pain, sensory impairment, and living in a nursing home or hostel). Only 21 of 923 elderly persons reported repeatedly having had a wish to die during the previous two weeks. Although the wish to die was associated with depression, there were several other factors also associated with it independently of depression: not being married, poor self-rated health, disability, pain, hearing impairment, visual impairment, living in a nursing home or hostel. A small minority expressed the wish to die but had a normal mood state. It was concluded that the wish to die is associated with several factors in addition to depression and may be present in individuals with few depressive symptoms. There is a need to investigate whether factors associated with the wish to die are treatable and whether this can restore the desire to live.

122 citations


Journal ArticleDOI
TL;DR: To estimate the prevalence of persistent insomnia and its correlates in samples of people living in the community and in institutional settings, data are collected on adults in the Netherlands over a 10-year period in order to establish a baseline for this study.
Abstract: OBJECTIVE To estimate the prevalence of persistent insomnia and its correlates in samples of people living in the community and in institutional settings. METHODS Respondents were interviewed in their place of residence by trained interviewers using the Canberra Interview for the Elderly, a structured psychiatric examination. RESULTS Information about sleeping habits was obtained from 874 community and 59 institutional residents. Insomnia was persistent in 16% of the community-dwelling population and 12% of the institutional residents, with 15% and 40%, respectively, regularly taking a hypnotic. Of those without insomnia, 10% in the community but over a third in institutions were using a hypnotic. Insomnia was associated with depression, pain and poor physical health. CONCLUSIONS Persistent insomnia in the elderly, as in other age groups, is strongly associated with depressed mood, as well as with physical disease. Because of this, insomnia should not be dismissed as a normal part of ageing, and therefore ignored as a significant symptom. Continued surveillance is needed in general practice, geriatric services and nursing homes of the routine use of hypnotics by the elderly.

73 citations


Journal ArticleDOI
TL;DR: Findings call into question the validity of the ICD-10 diagnosis of MCD, which was predicted by a report that memory or intelligence interfered with daily life but not by performance on cognitive tests or by report of physical illness.
Abstract: Criteria for the diagnosis of ICD-10 Mild Cognitive Disorder (MCD) were applied to a sample of 897 community dwelling elderly participants. Criterion A (the presence of a physical disorder) was met by 44%, Criterion B (report of a cognitive disorder) by 17%, Criterion C (an abnormality in quantified cognitive assessments) by 60%, and Criterion D (exclusion on basis of dementia and other conditions) by 74%. A total of 36 cases (4%) met all four criteria. Correlations between Criteria A and B, and B and C were weak (r = 0.18), and the correlation between Criteria A and C was almost zero (r = 0.02). This suggests that no syndrome exists. Membership of MCD was predicted by a report that memory or intelligence interfered with daily life but not by performance on cognitive tests or by a report of physical illness. Cases of MCD had higher anxiety, depression and neuroticism scores than normal elderly, but did not differ substantially on tests of cognitive functioning. These findings call into question the validity of the ICD-10 diagnosis of MCD.

42 citations


Journal ArticleDOI
TL;DR: A latent trait model was fitted to the responses of a large probability sample of elderly Australians to the short form of the Eysenck Personality Questionnaire-Revised (EPQ-R) as discussed by the authors.

13 citations