H
Helen L. Gerns
Researcher at University of California, San Francisco
Publications - 3
Citations - 279
Helen L. Gerns is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Bartonella & Bartonella quintana. The author has an hindex of 3, co-authored 3 publications receiving 264 citations.
Papers
More filters
Journal ArticleDOI
Bacteremia, fever, and splenomegaly caused by a newly recognized bartonella species.
Marina E. Eremeeva,Helen L. Gerns,Shari L. Lydy,Jeanna S. Goo,Edward T. Ryan,Smitha S. Mathew,Mary Jane Ferraro,Judith M. Holden,William L. Nicholson,Gregory A. Dasch,Jane E. Koehler +10 more
TL;DR: A patient who had fever and splenomegaly after traveling to Peru and also had bacteremia from an organism that resembled Bartonella bacilliformis was described, which revealed that this fastidious bacterium represented a previously uncultured and unnamed bartonella species.
Journal ArticleDOI
Proteomic and immunoblot analyses of Bartonella quintana total membrane proteins identify antigens recognized by sera from infected patients.
Jenni K. Boonjakuakul,Helen L. Gerns,Yu Ting Chen,Linda D. Hicks,Michael F. Minnick,Scott E. Dixon,Steven C. Hall,Jane E. Koehler +7 more
TL;DR: In this article, the outer membrane subproteome of Bartonella quintana is defined and a two-dimensional sodium dodecyl sulfate-polyacrylamide gel electrophoresis and peptide mass fingerprinting is used to identify the predominant B. quintana antigens targeted by the human immune system during infection.
Journal ArticleDOI
A SacB Mutagenesis Strategy Reveals that the Bartonella quintana Variably Expressed Outer Membrane Proteins Are Required for Bloodstream Infection of the Host
TL;DR: The deletion of the entire vomp locus, but not the deletion of two vomp genes, results in a null mutant strain that is incapable of establishing bloodstream infection in vivo, and the Vomp adhesins represent critical virulence factors in vitro, warranting further study.