H
Helen M. I. Osborn
Researcher at University of Reading
Publications - 138
Citations - 3316
Helen M. I. Osborn is an academic researcher from University of Reading. The author has contributed to research in topics: Prodrug & Chemistry. The author has an hindex of 31, co-authored 129 publications receiving 2954 citations. Previous affiliations of Helen M. I. Osborn include Imperial College London & University of Oxford.
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Flavonoids as prospective compounds for anti-cancer therapy
TL;DR: The main molecular mechanisms of action of flavonoids attributing to their potential anti-cancer activities have been discussed and the key structural features required for their activity are highlighted.
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The asymmetric synthesis of aziridines
TL;DR: An overview of methods available for asymmetric preparation of a range of 1H- aziridines and their N-substituted analogues can be found in this article,.
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Recent advances in the construction of β-D-mannose and β-D-mannosamine linkages
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Neoglycolipid Probes Prepared via Oxime Ligation for Microarray Analysis of Oligosaccharide-Protein Interactions
Yan Liu,Ten Feizi,María Asunción Campanero-Rhodes,Robert A. Childs,Yibing Zhang,Barbara Mulloy,Philip G. Evans,Helen M. I. Osborn,Diana M. E. Otto,Paul R. Crocker,Wengang Chai +10 more
TL;DR: Evidence from NMR studies is provided that a significant proportion of the oxime-linked core monosaccharide is in the ring-closed form, and this form selectively interacts with a carbohydrate-binding protein.
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1,3-Dipolar cycloaddition reactions of carbohydrate derived nitrones and oximes
TL;DR: In this paper, a review aims to summarise key features of the synthesis and 1,3-dipolar cycloaddition reactions of carbohydrate derived nitrones and oximes, allowing access to oxazolines and isoxazolidines.