Helen Valsamis

TL;DR: The transition from translocation of PKC to formation of PKM may help to explain the molecular mechanisms of induction and maintenance of long-term potentiation.

TL;DR: A new form of protein kinase C (PKC) is described with a molecular weight of 97 kDa, higher than the known forms of vertebrate PKC, and is localized primarily in brain, in contrast to PKC eta, which is found predominantly in lung and skin.

TL;DR: The coexistence of Neuromyelitis Optica spectrum disorder (NMOSD) with other autoimmune diseases presents worse clinical outcomes and healthcare costs than NMOSD alone as discussed by the authors .

TL;DR: Quantitative analysis of EEG showed distinct slowing of brain rhythms in C19 patients compared to control, and machine learning algorithms showed consistently higher accuracy in the binary classification of patients as C19 versus control using EEG power for subjects below age 70 compared to older ones, providing further evidence for the more severe impact of SARS-CoV-2 on brain rhythm in younger individuals.

TL;DR: In this article , the authors developed a computational pipeline for the automated, rapid, high-throughput and objective analysis of electroencephalography (EEG) rhythms, and used this pipeline to define the quantitative EEG changes in patients with a PCR-positive diagnosis of CoV-2 (COVID19 or C19) in the intensive care unit (ICU) of Cleveland Clinic, compared to a group of age-matched PCR-negative (n = 38) control patients in the same ICU setting.