Showing papers in "Neuroscience Letters in 1993"

TL;DR: NIRS is a simple bedside technique for the assessment of hemodynamic alterations accompanying brain activation using near infrared spectroscopy and it is demonstrated that these findings are not due to alterations in skin blood flow.

TL;DR: It is shown that the medial prefrontal cortex plays an important role in the regulation of fear extinction in rats, a finding that may help elucidate the mechanisms and, possibly, the treatment of disorders of uncontrolled fear, such as anxiety, phobic, panic and posttraumatic stress disorders in humans.

TL;DR: It is demonstrated that neurons of both nuclei colocalize GABA with peptides in the IGL and SCN, and GABA should be considered the principal neurotransmitter of the circadian system.

TL;DR: Results indicate that processing ofβAPP to produce βAP occurs in the synaptic terminal field of axons and illustrate the utility of βAPP immunoreactivity as a general marker for axonal injury.

TL;DR: A trpE-fusion protein containing a C-terminal sequence of a rat metabotropic glutamate receptor, mGluR5, was used to produce an antibody as mentioned in this paper.

TL;DR: In this paper, changes in the oxygenation state of brain hemoglobin during mental work were monitored in real time (time resolution: 1 s) using near-infrared spectrophotometry in 14 healthy volunteers.

TL;DR: There is an apoptotic component to selective neuronal death following global ischemia in rat brain after a global cerebral ischemic insult produced by transient two vessel occlusion in rats.

TL;DR: It is suggested that during fixation most NADPH-diaphorase activity is inactivated and only some of the NAD PH- diaphorases activity associated with soluble nitric oxide synthase remains intact.

TL;DR: This selective modulation of the dynamic activity of mesolimbic dopamine neurons by the prefrontal cortex might be important in motivation, learning and schizophrenia.

TL;DR: The pattern of neuronal degeneration associated with neuritic AD pathology in both AD and PD may be an important basis of cognitive decline in both disorders.

TL;DR: It is found that new cells form in the subependymal layer and that they migrate subsequently into the olfactory bulbs where they acquire the nuclear morphology of granule cells and express neuron-specific markers.

TL;DR: Findings suggest that activation of serotonergic neurons in these brain regions is involved in the emotional and/or cognitive states in animals.

TL;DR: To test the hypothesis that painful stimuli to skeletal muscle lead to a widespread unmasking of synaptic connections in dorsal horn neurons, intramuscular injections of bradykinin were made outside the receptive fields (RFs) of these cells in the rat.

TL;DR: This study suggests that GABA, acting on GABAA subtype of receptors, is able to affect the development of the hippocampus.

TL;DR: The hypothesis that nitric oxide is a mediator in the coupling of cerebral blood flow to neuronal activation is tested and it is concluded that NO is involved in rCBF coupling to neuronalactivation.

TL;DR: It is shown that grip force is finely modulated in phase with load force during movements with grasped objects in which load force varies with acceleration, and concludes that in transporting an object, the programming of grip forces is part and parcel of the process of planning the arm movement.

TL;DR: Neurons that stain for NADPH diaphorase, which colocalizes with nitric oxide synthase (NOS), are scattered uniformly across neocortex, and denser in entorhinal cortex, whereas NOS-positive fibers are concentrated in layers IV and VI.

TL;DR: Results of the present study indicate that NO, produced by lesion-induced NOS, may be involved in and responsible for the neuronal death after traumatic injury.

TL;DR: It is concluded that in the contracting soleus spinal mechanisms (most likely Renshaw inhibition and MN afterhyperpolarization) contribute to the early part of the SP, while the late part ofThe SP is supraspinal (probably cortical) in origin.

TL;DR: It is found that the content of D-serine in the serum and cerebellum of mutant mice is much higher than that of normal mice, whereas a slight but significant difference in the cerebral D-Serine level is observed between the two strains.

TL;DR: Experimental tissue acidosis provides a controllable and harmless method to produce sustained, graded and spatially restricted pain and hyperalgesia to mechanical stimulation.

TL;DR: The results suggest that NMDA receptor activation may contribute to the mechanical hyperalgesia that follows peripheral tissue inflammation.

TL;DR: The results of these experiments suggest that, in this system, Hb is a potent neurotoxin, and that Hb neurotoxicity may contribute to secondary injury processes after trauma and intracranial hemorrhage.

TL;DR: These neurones have morphological and physiological properties which make them well-suited to exert a widespread inhibitory control over the efferent output of layer II to the dentate gyrus.

TL;DR: Changes of NADPH-diaphorase reaction (NDP) and nitric oxide synthase immunoreactivity (NOS-IR) in neurons of dorsal root ganglia (DRG) were investigated following transection and ligation of rat sciatic nerve.

TL;DR: Although the diameter and conduction velocity of myelinated fibers in the sciatic nerve isolated from neurofilament-deficient quail ('quiver') were compared with those from wild quail, results indicate that the correlation between the parameters observed in wild quails is still preserved.

TL;DR: The results suggested that up-regulation of the mRNA for CCK in primary afferents after nerve injury may be related to the clinical phenomenon of opioid insensitivity, and coadministration of CCK antagonists in combination with opioids may offer a new approach in treating neuropathic pain.

TL;DR: The findings suggest that extrinsic rather than intrinsic (tracheal and peribronchial) neurons are the source of NO release from guinea pig airway nerve fibres after electrical field stimulation.

TL;DR: It seems that some molecular disturbances such as ubiquitin play a role in the formation of the constricted and unconstricted filaments in Bunina bodies in anterior horn cells of patients with amyotrophic lateral sclerosis.

TL;DR: This is the first demonstration of cytokine receptor mRNA expression in isolated glial and neuronal cells by the RT-PCR method.