H
Helga C. Schaller
Researcher at Graz University of Technology
Publications - 9
Citations - 1720
Helga C. Schaller is an academic researcher from Graz University of Technology. The author has contributed to research in topics: Insulin & Insulin lispro. The author has an hindex of 7, co-authored 9 publications receiving 1597 citations. Previous affiliations of Helga C. Schaller include University of Cambridge & University of Graz.
Papers
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Journal ArticleDOI
Nonlinear model predictive control of glucose concentration in subjects with type 1 diabetes
Roman Hovorka,Valentina Canonico,Ludovic J. Chassin,Ulrich Haueter,Massimo Massi-Benedetti,Marco Orsini Federici,Thomas R. Pieber,Helga C. Schaller,Lukas Schaupp,Thomas Vering,Malgorzata E. Wilinska +10 more
TL;DR: Adapt nonlinear model predictive control is promising for the control of glucose concentration during fasting conditions in subjects with type 1 diabetes.
Journal ArticleDOI
Insulin kinetics in type-1 diabetes: continuous and bolus delivery of rapid acting insulin
Malgorzata E. Wilinska,Ludovic J. Chassin,Helga C. Schaller,Lukas Schaupp,Thomas R. Pieber,Roman Hovorka +5 more
TL;DR: Models representing the dependence of insulin absorption rate on insulin disappearance and the remote insulin effect on its volume of distribution could not be validated suggesting that these effects are not present or cannot be detected during physiological conditions.
Journal ArticleDOI
Closing the loop: the adicol experience.
Roman Hovorka,Ludovic J. Chassin,Malgorzata E. Wilinska,Valentina Canonico,Joyce Akwe Akwi,Marco Orsini Federici,Massimo Massi-Benedetti,Ivo Hutzli,Claudio Zaugg,Heiner Kaufmann,Marcel Both,Thomas Vering,Helga C. Schaller,Lukas Schaupp,Manfred Bodenlenz,Thomas R. Pieber +15 more
TL;DR: A subset of ADICOL activities focusing on the development of a glucose controller for semi-closed-loop control, an in silico testing environment, clinical testing, and system integration are described.
Journal ArticleDOI
On-line adaptive algorithm with glucose prediction capacity for subcutaneous closed loop control of glucose: evaluation under fasting conditions in patients with Type 1 diabetes
Helga C. Schaller,Helga C. Schaller,Lukas Schaupp,Lukas Schaupp,Manfred Bodenlenz,Manfred Bodenlenz,Malgorzata E. Wilinska,Ludovic J. Chassin,Paul Wach,Thomas Vering,Roman Hovorka,Thomas R. Pieber +11 more
TL;DR: An algorithm with glucose prediction capacity and continuous adaptation of patient parameters—a model predictive control (MPC) algorithm—to control blood glucose concentration during fasting conditions in patients with Type 1 diabetes is evaluated.
Journal ArticleDOI
Measurement of interstitial insulin in human adipose and muscle tissue under moderate hyperinsulinemia by means of direct interstitial access.
Manfred Bodenlenz,Lukas Schaupp,Tatjana Druml,Romana Sommer,Andrea Wutte,Helga C. Schaller,Frank Sinner,Paul Wach,Thomas R. Pieber +8 more
TL;DR: The data suggest that the concentrations of insulin arising in healthy subjects at the level of ISF per se are comparable between subcutaneous adipose and skeletal muscle tissue, and seem to confirm reports of low peripheral insulin levels during moderate insulin clamps.