Henri Schmitt

TL;DR: Results support an α-adrenergic component in the inhibitory effect of catapresan on vasomotor centres and in dogs, decrease in blood pressure, heart rate and aortic blood flow induced by intracisternal injection of piperoxane was reduced or reversed.

TL;DR: Morphinomimetic peptides were injected into the cisterna magna of chloralosed dogs and induced an initial and transient increase in blood pressure and heart rate followed by a delayed hypotension and bradycardia.

TL;DR: The central action of St 155 was confirmed and the medulla oblongata was found to be the main site of this action, and it was suggested that this long latency period was due to the slow passage of the drug from the cerebro spinal fluid into the nervous tissue.

TL;DR: At low doses, S.T. 155 decreased strikingly the discharges in the splanchnic and inferior cardiac nerves; this was also obtained in debuffered animals and reduced sympathetic tone appeared to be the cause of the fall in blood pressure.

TL;DR: In this article, the influence of 2-(2,6-dichlorophenylamino)-2-imidazoline hydrochloride (ST 155) on spontaneous discharges of sympathetic nerve and on evoked discharges elicited by chemostimulant drugs or electrical stimulation of sympathetic structures of the brain stem was investigated.