H
Herman Tse
Researcher at University of Hong Kong
Publications - 104
Citations - 6481
Herman Tse is an academic researcher from University of Hong Kong. The author has contributed to research in topics: Virus & Influenza A virus. The author has an hindex of 42, co-authored 97 publications receiving 5752 citations. Previous affiliations of Herman Tse include Queen Mary University of London & Guangzhou Institutes of Biomedicine and Health.
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Journal ArticleDOI
Interspecies transmission and emergence of novel viruses: lessons from bats and birds.
TL;DR: Bats and birds are natural reservoirs for providing viral genes during evolution of new virus species and viruses for interspecies transmission and the increased intrusion of humans into wildlife habitats and overcrowding of different wildlife species in wet markets and farms have facilitated the inter species transmission.
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Coronavirus HKU1 and Other Coronavirus Infections in Hong Kong
Susanna K. P. Lau,Patrick C. Y. Woo,Cyril C. Y. Yip,Herman Tse,Hoi-Wah Tsoi,Vincent C.C. Cheng,Paul P. Lee,Bone S.F. Tang,Chris H. Y. Cheung,Rodney A. Lee,Lok-Yee So,Yu-Lung Lau,Kwok-Hung Chan,Kwok-Yung Yuen +13 more
TL;DR: In this 12-month prospective study, nasopharyngeal aspirates from patients with acute respiratory tract infections were subjected to reverse transcription-PCRs specific for CoV-HKU1 and human coronaviruses NL63, OC43, and 229E, and upper respiratory infection was the most common presentation.
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Delayed Clearance of Viral Load and Marked Cytokine Activation in Severe Cases of Pandemic H1N1 2009 Influenza Virus Infection
Kelvin K. W. To,Ivan Hung,Iris W. S. Li,Kar-Lung Lee,Chi-Kwan Koo,Wing-Wa Yan,Raymond W. Liu,Ka-Ying Ho,Kwok-Hong Chu,Chi-Leung Watt,Wei-Kwang Luk,Kang-Yiu Lai,Fu-Loi Chow,Thomas Y.W. Mok,Tom Buckley,Jasper Fuk-Woo Chan,Samson S. Y. Wong,Bo-Jian Zheng,Honglin Chen,Candy C. Y. Lau,Herman Tse,Vincent C.C. Cheng,Kwok-Hung Chan,Kwok-Yung Yuen +23 more
TL;DR: The slower control of viral load and immunodysregulation in severe cases mandate the search for more effective antiviral and immunomodulatory regimens to stop the excessive cytokine activation resulting in ARDS and death.
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Ecoepidemiology and Complete Genome Comparison of Different Strains of Severe Acute Respiratory Syndrome-Related Rhinolophus Bat Coronavirus in China Reveal Bats as a Reservoir for Acute, Self-Limiting Infection That Allows Recombination Events
Susanna K. P. Lau,Kenneth S. M. Li,Yi Huang,Chung Tong Shek,Herman Tse,Ming Wang,Garnet K. Y. Choi,Huifang Xu,Carol S. F. Lam,Rongtong Guo,Kwok-Hung Chan,Bo-Jian Zheng,Patrick C. Y. Woo,Kwok-Yung Yuen +13 more
TL;DR: The present data suggest that SARSr-Rh-BatCoV causes acute, self-limiting infection in horseshoe bats, which serve as a reservoir for recombination between strains from different geographical locations within reachable foraging range.
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Molecular Epidemiology of Human Coronavirus OC43 Reveals Evolution of Different Genotypes over Time and Recent Emergence of a Novel Genotype due to Natural Recombination
Susanna K. P. Lau,Paul P. Lee,Alan K.L. Tsang,Cyril C. Y. Yip,Herman Tse,Rodney A. Lee,Lok-Yee So,Yu-Lung Lau,Kwok-Hung Chan,Patrick C. Y. Woo,Kwok-Yung Yuen +10 more
TL;DR: This represents the first study to describe natural recombination in HCoV-OC43 and the evolution of different genotypes over time, leading to the emergence of novel genotype D, which is associated with pneumonia in the authors' elderly population.