H
Hermann E. Gaub
Researcher at Ludwig Maximilian University of Munich
Publications - 294
Citations - 34126
Hermann E. Gaub is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Force spectroscopy & Microscopy. The author has an hindex of 82, co-authored 291 publications receiving 32148 citations. Previous affiliations of Hermann E. Gaub include Technische Universität München & University of Pau and Pays de l'Adour.
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Journal ArticleDOI
Reversible Unfolding of Individual Titin Immunoglobulin Domains by AFM
TL;DR: Single-molecule atomic force microscopy was used to investigate the mechanical properties of titin, the giant sarcomeric protein of striated muscle, and refolding of immunoglobulin domains was observed.
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Adhesion forces between individual ligand-receptor pairs.
TL;DR: Under conditions that allowed only a limited number of molecular pairs to interact, the force required to separate tip and bead was found to be quantized in integer multiples of 160 +/- 20 piconewtons for biotin and 85 +/- 15 piconewstons for iminobiotin.
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Cytotoxicity of colloidal CdSe and CdSe/ZnS nanoparticles.
Christian Kirchner,Tim Liedl,Stefan Kudera,Teresa Pellegrino,Almudena Muñoz Javier,Hermann E. Gaub,Sonja Stölzle,Niels Fertig,Wolfgang J. Parak +8 more
TL;DR: The data suggest that in addition to the release of toxic Cd(2+) ions from the particles also their surface chemistry, in particular their stability toward aggregation, plays an important role for cytotoxic effects.
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Single Molecule Force Spectroscopy on Polysaccharides by Atomic Force Microscopy
TL;DR: Dextran filaments linked to a gold surface were probed with the atomic force microscope tip by vertical stretching and the conformational change was found to be reversible and was corroborated by molecular dynamics calculations.
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How Strong Is a Covalent Bond
Michel Grandbois,Martin K. Beyer,Matthias Rief,Matthias Rief,Hauke Clausen-Schaumann,Hermann E. Gaub +5 more
TL;DR: The rupture force of single covalent bonds under an external load was measured with an atomic force microscope (AFM) and calculations that were based on density functional theory corroborate the measured values.