H
Hervé Cheradame
Researcher at University of Évry Val d'Essonne
Publications - 77
Citations - 1553
Hervé Cheradame is an academic researcher from University of Évry Val d'Essonne. The author has contributed to research in topics: Cationic polymerization & Polymerization. The author has an hindex of 19, co-authored 76 publications receiving 1406 citations. Previous affiliations of Hervé Cheradame include Université Paris-Saclay & University of Orléans.
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Journal ArticleDOI
Synthesis of linear polyethylenimine derivatives for DNA transfection.
Blandine Brissault,Antoine Kichler,Christine Guis,Christian Leborgne,Olivier Danos,Hervé Cheradame +5 more
TL;DR: It is demonstrated that the high transfection efficiency of polyethylenimines does not solely rely on their capacity to capture protons which are transferred into the endo-lysosomes during acidification.
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Nuclear delivery of NFκB-assisted DNA/polymer complexes: plasmid DNA quantitation by confocal laser scanning microscopy and evidence of nuclear polyplexes by FRET imaging
Gilles Breuzard,Magdalena Tertil,Cristine Gonçalves,Hervé Cheradame,Philippe Géguan,Chantal Pichon,Patrick Midoux +6 more
TL;DR: Data from FRET experiments strongly support a nuclear import of p3NF-luc3NF mediated by NFκB, and raise the question of their passage through the nuclear pore complex and their impact on the gene-expression efficiency.
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Gene transfer by chemical vectors, and endocytosis routes of polyplexes, lipoplexes and lipopolyplexes in a myoblast cell line.
Ludivine Billiet,Jean-Pierre Gomez,Mathieu Berchel,Paul-Alain Jaffrès,Tony Le Gall,Tristan Montier,Emilie Bertrand,Hervé Cheradame,Philippe Guégan,Mathieu Mével,Bruno Pitard,Thierry Benvegnu,Pierre Lehn,Chantal Pichon,Patrick Midoux +14 more
TL;DR: This study shows also that engineered cells expressing specific fluorescent compartments are convenient tools to monitor endocytosis of a fluorescent plasmid DNA by real time fluorescence confocal microscopy.
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Histidinylated linear PEI: a new efficient non-toxic polymer for gene transfer
Emilie Bertrand,Cristine Gonçalves,Ludivine Billiet,Jean Pierre Gomez,Chantal Pichon,Hervé Cheradame,Patrick Midoux,Philippe Guégan +7 more
TL;DR: A series of linear polyethylenimine substituted with histidine residue (His-lPEI) was synthesized using the Michael reaction in order to provide new highly efficient vectors for gene therapy applications with remarkable low cytotoxicity compared to lPEI-based polyplexes.
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Variation of the mesh size of PEO-based networks filled with TFSILi: from an Arrhenius to WLF type conductivity behavior
TL;DR: In this article, the properties of ionically conducting membranes based on polyethylene oxide (PEO) networks crosslinked with urethane functions, containing lithium bis(trifluoromethane sulfone imide) (TFSILi), were analyzed.