H
Hirofumi Yoshino
Researcher at Kagoshima University
Publications - 72
Citations - 2842
Hirofumi Yoshino is an academic researcher from Kagoshima University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 26, co-authored 59 publications receiving 2526 citations.
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Journal ArticleDOI
The tumour-suppressive function of miR-1 and miR-133a targeting TAGLN2 in bladder cancer
Hirofumi Yoshino,Takeshi Chiyomaru,Hideki Enokida,Kazumori Kawakami,S. Tatarano,Kenryu Nishiyama,Nijiro Nohata,Naohiko Seki,Masayuki Nakagawa +8 more
TL;DR: The downregulation ofmiR-1 and miR-133a was a frequent event in BC, and these miRNAs were recognised as tumour suppressive and TAGLN2 may be a target of both mi RNAs and had a potential oncogenic function.
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Aberrant expression of microRNAs in bladder cancer
Hirofumi Yoshino,Naohiko Seki,Toshihiko Itesako,Takeshi Chiyomaru,Masayuki Nakagawa,Hideki Enokida +5 more
TL;DR: Understanding the role of differentially expressed miRNAs, as well as their molecular targets, in bladder cancer will provide an effective and promising strategy for miRNA-based therapeutics for the treatment of bladder cancer.
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MiR-96 and miR-183 detection in urine serve as potential tumor markers of urothelial carcinoma: correlation with stage and grade, and comparison with urinary cytology
Yasutoshi Yamada,Hideki Enokida,Satoko Kojima,Kazumori Kawakami,Takeshi Chiyomaru,Shuichi Tatarano,Hirofumi Yoshino,Kazuya Kawahara,Kenryu Nishiyama,Naohiko Seki,Masayuki Nakagawa +10 more
TL;DR: MiR‐96 and miR‐183 in urine are promising tumor markers for UC and may be a good diagnostic marker in combination with urinary cytology.
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Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase ( PNP ) in prostate cancer
Satoko Kojima,Takeshi Chiyomaru,Kazumori Kawakami,Hirofumi Yoshino,Hideki Enokida,Nijiro Nohata,Miki Fuse,Tomohiko Ichikawa,Yukio Naya,Masayuki Nakagawa,Naohiko Seki +10 more
TL;DR: The PNP is a novel target gene of both miRNAs and potentially functions as an oncogene and may provide new insights into the underlying causes of PCa oncogenesis, which is a frequent event in PCa and both function as tumour suppressors.
Journal ArticleDOI
Tumor suppressive microRNA-1285 regulates novel molecular targets: Aberrant expression and functional significance in renal cell carcinoma
Hideo Hidaka,Naohiko Seki,Hirofumi Yoshino,Takeshi Yamasaki,Yasutoshi Yamada,Nijiro Nohata,Miki Fuse,Masayuki Nakagawa,Hideki Enokida +8 more
TL;DR: Downregulation of tumor suppressive miR-1285, which targets oncogenic genes including TGM2, might contribute to RCC development and provides new insights into potential mechanisms of RCC oncogenesis.