Tomohiko Ichikawa

TL;DR: A gene from human chromosome 11p11.2 was isolated and was shown to suppress metastasis when introduced into rat AT6.1 prostate cancer cells.

TL;DR: The PNP is a novel target gene of both miRNAs and potentially functions as an oncogene and may provide new insights into the underlying causes of PCa oncogenesis, which is a frequent event in PCa and both function as tumour suppressors.

TL;DR: Results suggest that a decreased expression of E-cadherin is associated with the progression of prostatic cancer.

TL;DR: Genetic diagnosis and/or molecular-targeted therapy via AR pathways can be developed for hormone-refractory states and several co-factors between ARs and the transcriptional complex have been cloned and reports indicate that steroid receptor co-activator 1 is correlated with the hormone- Refractory progression of prostate cancer.

TL;DR: Using the PC cell lines, gain-of-function assays revealed that miR-145 transfection inhibited cell proliferation, migration and invasion, implying that FSCN1 is associated with the progression of PC.