H
Hironori Ohde
Researcher at Osaka University
Publications - 15
Citations - 153
Hironori Ohde is an academic researcher from Osaka University. The author has contributed to research in topics: Plasma renin activity & Renin–angiotensin system. The author has an hindex of 9, co-authored 15 publications receiving 152 citations.
Papers
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Journal ArticleDOI
Hormonal responses to long‐term converting enzyme inhibition in hypertensive patients
Toshio Ogihara,Anna Maruyama,Takeshi Hata,Hiroshi Mikami,Mitsuaki Nakamaru,Toru Naka,Hironori Ohde,Yuichi Kumahara +7 more
TL;DR: It is concluded that another mechanism, such as enhancement of renal or local kinin‐prostaglandin system, as well as suppression of the renin‐angiotensin‐aldosterone system may be involved in the long‐term efficacy of captopril.
Journal ArticleDOI
Neuroprotective function of R-(-)-1-(benzofuran-2-yl)-2-propylaminopentane, [R-(-)-BPAP], against apoptosis induced by N-methyl(R)salsolinol, an endogenous dopaminergic neurotoxin, in human dopaminergic neuroblastoma SH-SY5Y cells.
Wakako Maruyama,Hong Yi,Tsutomu Takahashi,Seiichiro Shimazu,Hironori Ohde,Fumio Yoneda,Kinuko Iwasa,Makoto Naoi +7 more
TL;DR: The neuroprotective function of (-)-BPAP and the related compounds was examined against apoptosis induced by an endogenous neurotoxin, N-methyl( R)salsolinol [NM(R)Sal], a possible pathogenic toxin in Parkinson's disease, in human dopaminergic neuroblastoma SH-SY5Y cells.
Journal ArticleDOI
The Effect of Aging on Urinary Kallikrein Excretion in Normotensive Subjects and in Patients with Essential Hypertension
Toru Naka,Toshio Ogihara,Takeshi Hata,Anna Maruyama,Hiroshi Mikami,Mitsuaki Nakamaru,Seiji Gotoh,Kazuko Masuo,Hironori Ohde,Keiichi Iwanaga,Yuichi Kumahara +10 more
TL;DR: The age-related decrease of U(kal)V in normal subjects may be due to the reduced activity of the renin-angiotensin-aldosterone system, which is related to the pathogenesis or pathophysiology of essential hypertension.
Journal ArticleDOI
Responses of Active and Inactive Plasma Renin and Changes in Urinary Kallikrein and Plasma Prekallikrein to Various Conditions in Normal Subjects
Mitsuaki Nakamaru,Toshio Ogihara,Jitsuo Higaki,Takeshi Hata,Hironori Ohde,Toru Naka,Kazuko Masuo,Seiji Gotoh,Yuichi Kumahara,Kazuo Murakami +9 more
TL;DR: The present data suggest that the mechanisms ofr the control of inactive and active renin are different, and neither renal nor plasma kallikrein seems to be consistently involved in the in vivo activation of inactive renin.
Patent
Novel 2-(n-cyanoimino)thiazolidin-4-one derivatives
TL;DR: Novel 2-(N-cyanoimino)thiazolidin-4-one derivatives represented by general formula (I), which exhibit excellent cholesterollowering and triglyceride-lowering activities and are useful in the prevention or treatment of hyperlipidemia and diseases resulting therefrom.