Hiroshi Wachi

TL;DR: The effects of two synthetic elastin peptides VPGVG and VGVAPG, both of which are present in humanElastin molecules, are evaluated on the biosynthetic phenotype of extracellular matrix proteins and on the proliferation of human dermal fibroblasts.

TL;DR: In this article, a method and apparatus for automatically controlling arc welding is presented, in which pieces of optical information provided by at least two bands of different wavelengths of light radiated from a weld area being arc-welded under predetermined welding conditions are alternately picked up by an optical device to extract various weld factors representing the actual status of the weld area from these pieces of light information, and the extracted weld factors are compared with the desired values of the welding factors representing a desired status representing the desired status.

TL;DR: The findings suggest that moyamoya disease may result, at least in part, from an abnormal regulation of extracellular matrix metabolism that leads to increased steady state levels of elastin mRNA andElastin accumulation in the intimal thickening and that increased elast in accumulation is a stable marker of SMCs from patients with moy amoya disease.

TL;DR: Synthetic elastin peptides, VPGVG or its polymer (VPGVG) n , enhanced the proliferation of smooth muscle cells 1.5‐fold during 48 h treatment at the concetrations over 10−6 M or 1.0 μg/ml, respectively, which may reflect the feedback regulation ofElastin expression which may play an essential role in elastsin metabolism under the normal and diseased conditions.

TL;DR: The results indicate that dermal fibroblasts potentially express elafin on UV irradiation, UV-mediated elAFin interacts with elastin, and theElafin-elastin complex protects elastic fibers from elastolytic degradation, leading to the accumulation of elastic fibers in the actinic elastosis of sun-damaged skin.