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Akira Sato
Researcher at Iwaki Meisei University
Publications - 413
Citations - 6113
Akira Sato is an academic researcher from Iwaki Meisei University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 34, co-authored 380 publications receiving 5593 citations. Previous affiliations of Akira Sato include Tohoku University & Toshiba.
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Journal ArticleDOI
K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases
Hiroshi Kase,Kazuyuki Iwahashi,Satoshi Nakanishi,Yuzuru Matsuda,Koji Yamada,Mitsuru Takahashi,Chikara C O Patent De Murakata,Akira Sato,Masami Kaneko +8 more
TL;DR: K-252a was a non-selective inhibitor for these three protein kinases with Ki values 18-25 nM, whereas K-252b showed a comparable potency for protein kinase C (Ki, 20nM), whereas inhibitory potencies for cyclic nucleotide-dependentprotein kinases were reduced.
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Lack of acrosome formation in mice lacking a Golgi protein, GOPC.
Ryoji Yao,Chizuru Ito,Yasuko Natsume,Yoshinobu Sugitani,Hitomi Yamanaka,Shoji Kuretake,Kaoru Yanagida,Akira Sato,Kiyotaka Toshimori,Tetsuo Noda +9 more
TL;DR: Golgi-associated PDZ- and coiled-coil motif-containing protein (GOPC) provides important clues to understanding the mechanisms underlying spermatogenesis, and the GOPC-deficient mouse may be a unique and valuable model for human globozoospermia.
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MiR-148a attenuates paclitaxel resistance of hormone-refractory, drug-resistant prostate cancer PC3 cells by regulating MSK1 expression
Yasunori Fujita,Keitaro Kojima,Keitaro Kojima,Riyako Ohhashi,Nanako Hamada,Yoshinori Nozawa,Yoshinori Nozawa,Aya Kitamoto,Akira Sato,Shinji Kondo,Toshio Kojima,Takashi Deguchi,Masafumi Ito +12 more
TL;DR: The findings suggest that miR-148a plays multiple roles as a tumor suppressor and can be a promising therapeutic target for hormone-refractory prostate cancer especially for drug-resistant prostate cancer.
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Mechanism of activation of the Formin protein Daam1.
TL;DR: It is reported that Daam1 is not significantly activated by Rho binding but rather by its interaction with Dishevelled (Dvl), and the importance of a carboxyl-terminal binding partner, Dvl, that leads to the activation of Daam 1 is defined.
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Synthesis, Electrical Conductivity, and Crystal Structure of Cu4Sn7S16and Structure Refinement of Cu2SnS3
TL;DR: In this article, single-crystal X-ray data were used to determine the crystal structures of two spinel-type defects, namely, Cu4Sn7S16 and Cu2SnS3, and their crystal structures were determined by the conventional solid state reaction method.