H
Hitoshi Nakashima
Researcher at Fukuoka University
Publications - 179
Citations - 6041
Hitoshi Nakashima is an academic researcher from Fukuoka University. The author has contributed to research in topics: Kidney disease & Lupus erythematosus. The author has an hindex of 45, co-authored 166 publications receiving 5538 citations. Previous affiliations of Hitoshi Nakashima include Kagoshima University & University of Texas at Austin.
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Journal ArticleDOI
Proposal for diagnostic criteria for IgG4-related kidney disease
Mitsuhiro Kawano,Takako Saeki,Hitoshi Nakashima,Shinichi Nishi,Yutaka Yamaguchi,Satoshi Hisano,Nobuaki Yamanaka,Dai Inoue,Motohisa Yamamoto,Hiroki Takahashi,Hideki Nomura,Takashi Taguchi,Hisanori Umehara,Hirofumi Makino,Takao Saito +14 more
TL;DR: The provisional criteria and algorithm appear to be useful for clarifying the entity of IgG 4-RKD and seeking underlying IgG4- RKD cases; however, further experience is needed to confirm the validity of these criteria.
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Th1/Th2 balance of peripheral T helper cells in systemic lupus erythematosus
Mitsuteru Akahoshi,Hitoshi Nakashima,Yosuke Tanaka,Tsutomu Kohsaka,Shuji Nagano,Eiichi Ohgami,Yojiro Arinobu,Kunihiro Yamaoka,Hiroaki Niiro,Michiya Shinozaki,Hideki Hirakata,Takahiko Horiuchi,Takeshi Otsuka,Yoshiyuki Niho +13 more
TL;DR: Although SLE has been considered to be a disease in which Th2 cells predominate, the Th1/Th2 balance of peripheral Th cells in SLE patients in the present study did not show a predominance of these cells.
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The structure of arthropod hemocyanins.
Bernt Linzen,Nell M. Soeter,Austen Riggs,Hans-Jürgen Schneider,W. Schartau,M. D. Moore,E. Yokota,P. Q. Behrens,Hitoshi Nakashima,Toshiyuki Takagi,Takayuki K. Nemoto,Johan M. Vereijken,Henk J. Bak,Jaap J. Beintema,Anne Volbeda,W. P. J. Gaykema,Wim G. J. Hol +16 more
TL;DR: The polypeptide architecture of spiny lobster hemocyanin appears to be the same in all arthropods, and this structure must be at least as old as the estimated time of divergence of crustaceans and chelicerates, about 540 to 600 million years ago.
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Predominance of Th1 immune response in diffuse proliferative lupus nephritis.
Kohsuke Masutani,Mitsuteru Akahoshi,Kazuhiko Tsuruya,Masanori Tokumoto,Toshiharu Ninomiya,Tsutomu Kohsaka,Kyoichi Fukuda,Hidetoshi Kanai,Hitoshi Nakashima,Takeshi Otsuka,Hideki Hirakata +10 more
TL;DR: A predominance of Thl-type response in both peripheral and renal tissues of patients with DPLN is identified, suggesting that the peripheral blood Thl:Th2 ratio directly reflects the local histopathologic findings.
Journal ArticleDOI
Th2 and regulatory immune reactions contribute to IgG4 production and the initiation of Mikulicz disease
Akihiko Tanaka,Masafumi Moriyama,Hitoshi Nakashima,Katsuhisa Miyake,Jun Nosuke Hayashida,Takashi Maehara,Shouichi Shinozaki,Yoshiaki Kubo,Seiji Nakamura +8 more
TL;DR: The results suggest that the pathogenesis of Mikulicz disease is different from that of SS, a unique inflammatory disorder characterized by Th2 and regulatory immune reactions that might play key roles in IgG4 production.