H
HJ Dargie
Researcher at Western Infirmary
Publications - 26
Citations - 3563
HJ Dargie is an academic researcher from Western Infirmary. The author has contributed to research in topics: Heart failure & Myocardial infarction. The author has an hindex of 15, co-authored 26 publications receiving 3434 citations.
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Journal ArticleDOI
Effect of carvedilol on outcome after myocardial infarction in patients with left-ventricular dysfunction: the CAPRICORN randomised trial.
TL;DR: In patients treated long-term after an acute myocardial infarction complicated by left-ventricular systolic dysfunction, carvedilol reduced the frequency of all-cause and cardiovascular mortality, and recurrent, non-fatal myocardia infarctions.
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Plasma endothelin in chronic heart failure.
TL;DR: Evidence suggests that circulatory endothelin concentrations in the range 5–40 pmol/l are vasoactive, and may be of pathophysiological significance in patients with chronic heart failure.
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Increased concentrations of tumour necrosis factor in "cachectic" patients with severe chronic heart failure.
TL;DR: Circulating concentrations of tumour necrosis factor were increased in a significant proportion of patients with chronic heart failure and low body weight, and it may be a factor in the weight loss seen in patients with "cardiac cachexia".
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Redefinition of uremic cardiomyopathy by contrast-enhanced cardiac magnetic resonance imaging.
Patrick B. Mark,Patrick B. Mark,Nicola Johnston,B. A. Groenning,John E. Foster,Kevin G. Blyth,Thomas N. Martin,Tracey Steedman,HJ Dargie,Alan G. Jardine,Alan G. Jardine +10 more
TL;DR: It is shown that LVH is the predominant cardiomyopathy specific to uremia, while LV dilation and systolic dysfunction are due to underlying (possibly silent) ischemic heart disease.
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Morphine for the relief of breathlessness in patients with chronic heart failure—a pilot study
TL;DR: Morphine has long been used to relieve symptoms in acute failure, but there is little evidence about this potentially useful palliative therapy in CHF.