H
Ho-Joon Shin
Researcher at Ajou University
Publications - 110
Citations - 2170
Ho-Joon Shin is an academic researcher from Ajou University. The author has contributed to research in topics: Naegleria fowleri & Antibody. The author has an hindex of 24, co-authored 100 publications receiving 1810 citations.
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STAT3 transcriptional factor activated by reactive oxygen species induces IL6 in starvation-induced autophagy of cancer cells
Sarah Yoon,Sang Uk Woo,Jung Hee Kang,Kyongmin Kim,Myung-Hee Kwon,Sun Park,Ho-Joon Shin,Ho-Shin Gwak,Yong-Joon Chwae +8 more
TL;DR: It is found for the first time that JAK2/STAT3 was activated in HeLa cells when they were starved or treated with rapamycin, indicating that the autophagic process in cancer cells can contribute to their survival by JAk2/ STAT3 activation and subsequent secretion of growth factors.
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NF-κB and STAT3 cooperatively induce IL6 in starved cancer cells
TL;DR: Novel survival strategies of cancer cells are suggested by which two oncogenic transcriptional factors, NF-κB and STAT3, are activated simultaneously by an intrinsic mechanism during stressful conditions ofcancer cells, and they cooperatively induce various survival factors.
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In vitro inhibition of coronavirus replications by the traditionally used medicinal herbal extracts, Cimicifuga rhizoma, Meliae cortex, Coptidis rhizoma, and Phellodendron cortex.
Hye-Young Kim,Hyun-Soo Shin,Hyun Park,Youn-Chul Kim,Yong Gab Yun,Sun Park,Ho-Joon Shin,Kyongmin Kim,Kyongmin Kim +8 more
TL;DR: Traditional medicinal herbal extracts selected strongly inhibited MHV replication and could be potential candidates for new anti-coronavirus drugs.
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Seroprevalence of toxoplasmosis in Korean pregnant women
TL;DR: The seroprevalence of toxoplasmosis in pregnant women was found to be comparatively low, consistent with previous reports from Korea, however a variety of diagnostic tools were considered to be useful for the precise diagnosis of congenital toxoplasmaosis.
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Molecular mechanisms of biogenesis of apoptotic exosome-like vesicles and their roles as damage-associated molecular patterns.
Soo Jeong Park,Jeong Mi Kim,Jihyo Kim,Jaehark Hur,Sun Park,Kyongmin Kim,Ho-Joon Shin,Yong-Joon Chwae +7 more
TL;DR: Exosomal fractions called “apoptotic exosome-like vesicles” (AEVs) prepared from apoptotic-conditioned medium were the main inflammatory factors, suggesting AEVs could be key inflammatory mediators, acting as DAMPs that could explain the pathogeneses of various chronic inflammations, autoimmune diseases, or cancers in the future.