H
Homigol Biesiada
Researcher at University of Kansas
Publications - 5
Citations - 1140
Homigol Biesiada is an academic researcher from University of Kansas. The author has contributed to research in topics: Membrane lipids & Mass spectrometry. The author has an hindex of 5, co-authored 5 publications receiving 1022 citations.
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Journal ArticleDOI
Profiling Membrane Lipids in Plant Stress Responses ROLE OF PHOSPHOLIPASE Dα IN FREEZING-INDUCED LIPID CHANGES IN ARABIDOPSIS
Ruth Welti,Weiqi Li,Maoyin Li,Yongming Sang,Homigol Biesiada,Han-E Zhou,C.B. Rajashekar,Todd D. Williams,Xuemin Wang +8 more
TL;DR: Data suggest that PC, rather than PE and PG, is the majorin vivo substrate of PLDα, and the greater loss of PC and increase in PA in wild-type plants as compared with PLD α-deficient plants may be responsible for destabilizing membrane bilayer structure.
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Repair of oxidized calmodulin by methionine sulfoxide reductase restores ability to activate the plasma membrane Ca-ATPase.
TL;DR: The ability of CaMox isolated from senescent brain to fully activate the PM Ca-ATPase following repair byMsrA suggests the specific activity of MsrA is insufficient to maintain CaM function in aging brain, and the possible regulatory role MsRA may play in the modulation ofCaM function and calcium homeostasis under conditions of oxidative stress.
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Substrate reduction intervention by L-cycloserine in twitcher mice (globoid cell leukodystrophy) on a B6;CAST/Ei background.
TL;DR: In this article, substrate reduction therapy using l -cycloserine, an inhibitor of 3-ketodihydrosphingosine synthase, was examined in twitcher mice on a C57BL/6×CAST/Ei (B6;CAST)/Ei) background, which mimics a late onset variant of GCL.
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Delayed Clinical and Pathological Signs in Twitcher (Globoid Cell Leukodystrophy) Mice on a C57BL/6 × CAST/Ei Background
TL;DR: The introduction of modifier genes from the wild, inbred CAST/Ei strain had a phenotypic effect resulting in a significantly slower disease course.
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High sensitivity of Zn2+ insulin to metal-catalyzed oxidation: detection of 2-oxo-histidine by tandem mass spectrometry.
TL;DR: At a Zn2+/INS molar ratio comparable to that in regular INS preparations, Zn1+-INS was susceptible to MCO, with both His residues of INS converted partially to 2-oxo-His, with 10HisB possessing ca.