H
Hong Li
Researcher at Guangzhou University of Chinese Medicine
Publications - 23
Citations - 1282
Hong Li is an academic researcher from Guangzhou University of Chinese Medicine. The author has contributed to research in topics: Muscle hypertrophy & Angiotensin II. The author has an hindex of 14, co-authored 20 publications receiving 836 citations. Previous affiliations of Hong Li include Sun Yat-sen University & National Institutes of Health.
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Journal ArticleDOI
The orphan receptor NOR1 participates in isoprenaline-induced cardiac hypertrophy by regulating PARP-1.
Xiaojun Feng,Hui Gao,Hui Gao,Si Gao,Zhuoming Li,Hong Li,Jing Lu,Jiaojiao Wang,Xiaoyang Huang,Min Liu,Jian Zou,Jiantao Ye,Peiqing Liu +12 more
TL;DR: The roles of NOR1 in cardiac hypertrophy induced by isoprenaline and the underlying molecular mechanisms were investigated and its potential contribution to cardiovascular diseases remains to be assessed.
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Mitochondrial binding of α-enolase stabilizes mitochondrial membrane: its role in doxorubicin-induced cardiomyocyte apoptosis.
Si Gao,Hong Li,Yi Cai,Jiantao Ye,Zhiping Liu,Jing Lu,Xiaoyang Huang,Xiaojun Feng,Hui Gao,Shaorui Chen,Min Li,Peiqing Liu +11 more
TL;DR: The present study indicates that mitochondria-located α-enolase has a beneficial role in stabilizing mitochondrial membrane, and in cardiomyocytes, the displacement of α- enolase from mitochondria by doxorubicin may involve in activation of the intrinsic cell death pathway.
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COX-2 is involved in ET-1-induced hypertrophy of neonatal rat cardiomyocytes: role of NFATc3.
Hong Li,Si Gao,Jiantao Ye,Xiaojun Feng,Yi Cai,Zhiping Liu,Jing Lu,Qin Li,Xiaoyang Huang,Shaorui Chen,Peiqing Liu +10 more
TL;DR: In the cultured rat neonatal cardiomyocytes, ET-1 significantly upregulated the expression and activity of COX-2, which was accompanied by increase in cell surface area and BNP mRNA level, and this report suggested a potential therapeutic strategy against cardiac hypertrophy by inhibiting COx-2.
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Histone Deacetylases (HDACs) and Atherosclerosis: A Mechanistic and Pharmacological Review.
Xiaona Chen,Yanhong He,Wenjun Fu,Amirhossein Sahebkar,Amirhossein Sahebkar,Yuhui Tan,Suowen Xu,Hong Li +7 more
TL;DR: An updated view on the roles of HDACs (Class I, Class II, Class IV) and HDAC inhibitors in vascular dysfunction and AS is presented and the novel therapeutic targets and agents in atherosclerotic cardiovascular diseases are elaborate.
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Dkk1 exacerbates doxorubicin-induced cardiotoxicity by inhibiting the Wnt/β-catenin signaling pathway.
Liying Liang,Yalin Tu,Jing Lu,Panxia Wang,Zhen Guo,Qianqian Wang,Kaiteng Guo,Rui Lan,Hong Li,Peiqing Liu +9 more
TL;DR: The crucial role of the Dkk1–Wnt/β-catenin signaling axis has a crucial role in Dox-induced cardiotoxicity, suggesting a potential therapeutic approach for treatment of cardiomyopathy caused by clinical use of Dox.