H
Hong Yan Dai
Researcher at Chinese Ministry of Education
Publications - 2
Citations - 168
Hong Yan Dai is an academic researcher from Chinese Ministry of Education. The author has contributed to research in topics: Angiotensin-converting enzyme 2 & Ventricular remodeling. The author has an hindex of 2, co-authored 2 publications receiving 153 citations.
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Journal ArticleDOI
Angiotensin-converting enzyme-2 overexpression improves left ventricular remodeling and function in a rat model of diabetic cardiomyopathy.
Bo Dong,Qing Tao Yu,Hong Yan Dai,Yan Yan Gao,Zhao Li Zhou,Lei Zhang,Hong Jiang,Fei Gao,Shu Ying Li,Yue Hui Zhang,Hong Jun Bian,Chun Xi Liu,Nan Wang,Hui Xu,Chun Ming Pan,Huai Dong Song,Cheng Zhang,Yun Zhang +17 more
TL;DR: ACE2 inhibits myocardial collagen accumulation and improves LV remodeling and function in a rat model of diabetic cardiomyopathy, and provides a promising approach to the treatment of patients with diabetes.
Journal ArticleDOI
ACE2 Overexpression Ameliorates Left Ventricular Remodeling and Dysfunction in a Rat Model of Myocardial Infarction
Yu Xia Zhao,Hui Qiu Yin,Qing Tao Yu,Yun Qiao,Hong Yan Dai,Ming Xiang Zhang,Lei Zhang,Yun Fang Liu,Lai Cheng Wang,De Shan Liu,Bi Ping Deng,Yue Hui Zhang,Chun Ming Pan,Huai Dong Song,Xun Qu,Hong Jiang,Chun Xi Liu,Xiao Ting Lu,Bin Liu,Fei Gao,Bo Dong +20 more
TL;DR: In conclusion, overexpression of ACE2 favorably affected the pathological process of LV remodeling after MI by inhibiting ACE activity, reducing AngII levels, and up-regulating Ang-(1-7) expression, thus providing a potential therapeutic target in the treatment of heart failure.