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Bi Ping Deng
Publications - 3
Citations - 303
Bi Ping Deng is an academic researcher. The author has contributed to research in topics: Angiotensin-converting enzyme 2 & Angiotensin II. The author has an hindex of 3, co-authored 3 publications receiving 274 citations.
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Journal ArticleDOI
Overexpression of ACE2 Enhances Plaque Stability in a Rabbit Model of Atherosclerosis
Bo Dong,Cheng Zhang,Jing Bo Feng,Yu Xia Zhao,Shu Ying Li,Ya Pei Yang,Qiu Li Dong,Bi Ping Deng,Li Zhu,Qing Tao Yu,Chun Xi Liu,Bin Liu,Chun Ming Pan,Huai Dong Song,Ming Xiang Zhang,Yun Zhang +15 more
TL;DR: Overexpression of ACE2 results in stabilized atherosclerotic plaques and the mechanism is probably the conversion of vasoconstrictive angiotensin II to vessel protective angiotENSin 1–7.
Journal ArticleDOI
Angiotensin-converting enzyme 2 attenuates atherosclerotic lesions by targeting vascular cells
Cheng Zhang,Yu Xia Zhao,Yue Hui Zhang,Li Zhu,Bi Ping Deng,Zhao Li Zhou,Shu Ying Li,Xiao Ting Lu,Li Li Song,Xue Ming Lei,Wen Bo Tang,Nan Wang,Chun Ming Pan,Huai Dong Song,Chun Xi Liu,Bo Dong,Yun Zhang,Yihai Cao +17 more
TL;DR: It is shown that ACE2 inhibited the development of early atherosclerotic lesions by suppressing the growth of vascular smooth muscle cells (VSMCs) and improving endothelial function and suggested that modulation of ACE2 could offer a therapeutic option for treating atherosclerosis.
Journal ArticleDOI
ACE2 Overexpression Ameliorates Left Ventricular Remodeling and Dysfunction in a Rat Model of Myocardial Infarction
Yu Xia Zhao,Hui Qiu Yin,Qing Tao Yu,Yun Qiao,Hong Yan Dai,Ming Xiang Zhang,Lei Zhang,Yun Fang Liu,Lai Cheng Wang,De Shan Liu,Bi Ping Deng,Yue Hui Zhang,Chun Ming Pan,Huai Dong Song,Xun Qu,Hong Jiang,Chun Xi Liu,Xiao Ting Lu,Bin Liu,Fei Gao,Bo Dong +20 more
TL;DR: In conclusion, overexpression of ACE2 favorably affected the pathological process of LV remodeling after MI by inhibiting ACE activity, reducing AngII levels, and up-regulating Ang-(1-7) expression, thus providing a potential therapeutic target in the treatment of heart failure.