H
Hongquan Duan
Researcher at Tianjin Medical University
Publications - 10
Citations - 741
Hongquan Duan is an academic researcher from Tianjin Medical University. The author has contributed to research in topics: Drug carrier & Controlled release. The author has an hindex of 8, co-authored 10 publications receiving 668 citations.
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Journal ArticleDOI
Multi-functionalized graphene oxide based anticancer drug-carrier with dual-targeting function and pH-sensitivity
Xiaoying Yang,Yinsong Wang,Xin Huang,Yanfeng Ma,Yi Huang,Rongcun Yang,Hongquan Duan,Yongsheng Chen +7 more
TL;DR: The results show that this multi-functionalized GO has potential applications for targeted delivery and the controlled release of anticancer drugs.
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The preparation of functionalized graphene oxide for targeted intracellular delivery of siRNA
TL;DR: It was found that functionalized graphene oxide could target the HeLa in vitro and the transfected hTERT siRNA could knockdown the protein expression level and mRNA level efficiently.
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Hyaluronic Acid Stabilized Iodine-Containing Nanoparticles with Au Nanoshell Coating for X-ray CT Imaging and Photothermal Therapy of Tumors.
Xinghua Liu,Chunhui Gao,Junheng Gu,Yunfang Jiang,Xinlin Yang,Shao-Yong Li,Wei Gao,Tong An,Hongquan Duan,Jingwei Fu,Yinsong Wang,Xiaoying Yang +11 more
TL;DR: PMATIB/PEI/Au nanoshell/HA nanoparticles displayed a great potential for CT diagnosis and CT-guided, focused photothermal tumor therapy and demonstrated a facile but effective approach to synthesize biocompatible and well-dispersed multifunctional nanoparticles.
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Folic acid-conjugated graphene oxide as a transporter of chemotherapeutic drug and siRNA for reversal of cancer drug resistance
TL;DR: Cell experiments show that cellular uptake of fluorescein FAM-labeled DNA sequence (FAM-DNA) delivered by GO-FACO+ exhibits higher efficiency in doxorubicin chloride (Dox)-resistant MCF-7 human breast cancer cells with folate receptor overexpressed than that delivered by chitosan oligosaccharide (CO)-functionalized graphene oxides (GO-CO+) without folic acid modification.
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Functionalized Graphene Oxide with Hepatocyte Targeting as Anti-Tumor Drug and Gene Intracellular Transporters.
Xiufen Cao,Shuang Zheng,Sipei Zhang,Yinsong Wang,Xiaoying Yang,Hongquan Duan,Yi Huang,Yongshen Chen +7 more
TL;DR: The results showed that GO-LCO+ can deliver fluorescein FAM-labeled DNA sequence (FAM-DNA) into human hepatic carcinoma cells with higher efficiency than positively charged chitosan oligosaccharide (CO) functionalized graphene oxides (GO-CO+) without Lactose acid modification.