H
Hongxia Chen
Researcher at Jiangsu University
Publications - 13
Citations - 228
Hongxia Chen is an academic researcher from Jiangsu University. The author has contributed to research in topics: Lycium chinense & Oxidative stress. The author has an hindex of 7, co-authored 10 publications receiving 158 citations. Previous affiliations of Hongxia Chen include Chinese Academy of Sciences.
Papers
More filters
Journal ArticleDOI
Lycium chinense leaves extract ameliorates diabetic nephropathy by suppressing hyperglycemia mediated renal oxidative stress and inflammation
TL;DR: The results obtained in this study suggests that L. chinense leaf might have the potential as possible pharmacological agent against diabetic nephropathy by suppressing renal oxidative stress and inflammation.
Journal ArticleDOI
Anti-oxidative, anti-secretory and anti-inflammatory activities of the extract from the root bark of Lycium chinense (Cortex Lycii) against gastric ulcer in mice
TL;DR: Oral administration of ELC before ethanol-induced ulcer increased the gastric mucus content, restored the superoxide dismutase and glutathione levels, reduced malondialdehyde levels and inhibited the activity of myeloperoxidase, suggesting gastroprotective properties of L. chinense.
Journal ArticleDOI
Effect of the Polyphenol Rich Ethyl Acetate Fraction from the Leaves of Lycium chinenseMill. on Oxidative Stress, Dyslipidemia, and Diabetes Mellitus in Streptozotocin-Nicotinamide Induced Diabetic Rats.
TL;DR: The present study has revealed that L. chinenseMill possess anti‐hyperglycemic and anti-hyperlipidemic properties which is mediated through modulation of oxidative stress and polyphenolics might be responsible for the action.
Journal ArticleDOI
Neuroprotective effect of trans-N-caffeoyltyramine from Lycium chinense against H2O2 induced cytotoxicity in PC12 cells by attenuating oxidative stress
TL;DR: Investigation of the antioxidant effect of trans-N-caffeoyltyramine isolated from Cortex lycii against hydrogen peroxide induced cell damages in PC12 cells indicated that pretreatment with TNC before the exposure of cells to H2O2 toxicity lead to a significant increase in the cell viability and the antioxidant enzyme activities catalase, superoxide dismutase, glutathione, and reduced the level of malondialdehyde.
Journal ArticleDOI
Lycium chinensis Mill attenuates glutamate induced oxidative toxicity in PC12 cells by increasing antioxidant defense enzymes and down regulating ROS and Ca2+ generation
TL;DR: Substantial evidence is provided that L. chinensis Mill protected PC12 cells against glutamate-induced cell death by attenuating ROS generation, Ca(2+) influx, and increased the antioxidant defense capacity of PC 12 cells against oxidative stress damages, suggesting the possible potential of extracts from the plant as sources of bioactive molecules in the treatment of neurodegenerative disorders.