H
Hongxu Liu
Researcher at University of Massachusetts Amherst
Publications - 36
Citations - 470
Hongxu Liu is an academic researcher from University of Massachusetts Amherst. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 8, co-authored 18 publications receiving 310 citations. Previous affiliations of Hongxu Liu include Zhengzhou University.
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Journal ArticleDOI
I2-Mediated Oxidative C–O Bond Formation for the Synthesis of 1,3,4-Oxadiazoles from Aldehydes and Hydrazides
Wenquan Yu,Gang Huang,Yueteng Zhang,Hongxu Liu,Lihong Dong,Yu Xuejun,Li Yujiang,Junbiao Chang,Junbiao Chang +8 more
TL;DR: A practical and transition-metal-free oxidative cyclization of acylhydrazones into 1,3,4-oxadiazoles has been developed by employing stoichiometric molecular iodine in the presence of potassium carbonate.
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Synthesis of 2-amino-1,3,4-oxadiazoles and 2-amino-1,3,4-thiadiazoles via sequential condensation and I2-mediated oxidative C–O/C–S bond formation.
TL;DR: This transition-metal-free sequential synthesis process is compatible with aromatic, aliphatic, and cinnamic aldehydes, providing facile access to a variety of diazole derivatives bearing a 2-amino substituent in an efficient and scalable fashion.
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Regioselective synthesis of 3,4-disubstituted isocoumarins through the Pd-catalyzed annulation of 2-iodoaromatic acids with ynamides
TL;DR: A Pd(0)-catalyzed annulation reaction of ynamides is described for the efficient synthesis of 3,4-disubstituted isocoumarins, exhibiting excellent regioselectivities and a wide functional group tolerance.
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Blended Assemblies of Amphiphilic Random and Block Copolymers for Tunable Encapsulation and Release of Hydrophobic Guest Molecules
TL;DR: Self-assembly of amphiphilic polymers in aqueous solution builds up versatile carrier platforms for therapeutic delivery and provides “hydrophobic pockets” for the protection of againstcation by the immune system.
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Synthesis of 3-Substituted 2-Aminochromones via Sn(IV)-Promoted Annulation of Ynamides with 2-Methoxyaroyl Chlorides
TL;DR: This novel method allows for a concomitant construction of C-C and C-O bonds between ynamides and 2-methoxyaroyl chlorides by a tandem Friedel-Crafts acylation/oxo-Michael addition/elimination strategy.