H
Hoyoku Nishino
Researcher at Kyoto Prefectural University of Medicine
Publications - 380
Citations - 17892
Hoyoku Nishino is an academic researcher from Kyoto Prefectural University of Medicine. The author has contributed to research in topics: DMBA & Tumor promotion. The author has an hindex of 71, co-authored 380 publications receiving 16929 citations. Previous affiliations of Hoyoku Nishino include Osaka University of Pharmaceutical Sciences & Hiroshima University.
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Journal ArticleDOI
An antitumor promoter from Moringa oleifera Lam.
Amelia P. Guevara,Carolyn Vargas,Hiromu Sakurai,Yasuhiro Fujiwara,Keiji Hashimoto,Takashi Maoka,Mutzuo Kozuka,Yoshohiro Ito,Harukuni Tokuda,Hoyoku Nishino +9 more
TL;DR: Niazimicin was further subjected to in vivo test and found to have potent antitumor promoting activity in the two-stage carcinogenesis in mouse skin using 7,12-dimethylbenz(a)anthracene (DMBA) as initiator and TPA as tumor promoter.
Journal Article
Genistein arrests cell cycle progression at G2-M.
Yoshizumi Matsukawa,Nobuyuki Marui,Toshiyuki Sakai,Yoshiko Satomi,Mitsunori Yoshida,Katsuhiko Matsumoto,Hoyoku Nishino,Akira Aoike +7 more
TL;DR: Flow-cytometric analysis and microscopic observation suggest that the G2-M arrest by genistein is a unique effect among flavonoids.
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The effect of quercetin on cell cycle progression and growth of human gastric cancer cells.
Mitsumori Yoshida,Toshiyuki Sakai,Nobuko Hosokawa,Nobuyuki Marui,Katsuhiko Matsumoto,Akihiro Fujioka,Hoyoku Nishino,Akira Aoike +7 more
TL;DR: Quercetin markedly inhibited the growth of human gastric cancer cells and the IC 50 value was 32–55 μM, while DNA synthesis was suppressed to 14% of the control level by the treatment with 70 μM quercet in for 2 days.
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Production of bioactive triterpenes by Eriobotrya japonica calli.
Shoko Taniguchi,Yoko Imayoshi,Eri Kobayashi,Yoshie Takamatsu,Hideyuki Ito,Tsutomu Hatano,Hiroshi Sakagami,Harukuni Tokuda,Hoyoku Nishino,Daigo Sugita,Susumu Shimura,Takashi Yoshida +11 more
TL;DR: All of the triterpenes isolated from the callus tissues showed an inhibitory effect comparable to (-)-epigallocatechin gallate of green tea on the activation of Epstein-Barr virus early antigen (EBV-EA) induced by 12-O-tetradecanoylphorbol-13-acetate (TPA).
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Chemopreventive effects of carotenoids and curcumins on mouse colon carcinogenesis after 1,2-dimethylhydrazine initiation.
Jin Man Kim,Shunichi Araki,Dae Joong Kim,Cheol Beom Park,Nobuo Takasuka,Hiroyasu Baba-Toriyama,Tomonori Ota,Zohar Nir,Frederick Khachik,Nobuyoshi Shimidzu,Yoshito Tanaka,Toshihiko Osawa,Tetsuya Uraji,Michiaki Murakoshi,Hoyoku Nishino,Hiroyuki Tsuda +15 more
TL;DR: It is suggested that fucoxanthin, lutein, and THC may have potential as chemopreventive agents against colon carcinogenesis.