H
Hsin-Yao Tsai
Researcher at Taipei Veterans General Hospital
Publications - 12
Citations - 82
Hsin-Yao Tsai is an academic researcher from Taipei Veterans General Hospital. The author has contributed to research in topics: Gene & Single-nucleotide polymorphism. The author has an hindex of 3, co-authored 9 publications receiving 53 citations.
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Journal ArticleDOI
Role of the DLGAP2 gene encoding the SAP90/PSD-95-associated protein 2 in schizophrenia.
Jun-Ming Li,Chao-Lin Lu,Min-Chih Cheng,Sy-Ueng Luu,Shih-Hsin Hsu,Tsung-Ming Hu,Hsin-Yao Tsai,Chia-Hsiang Chen +7 more
TL;DR: The results indicate that DLGAP2 is a susceptible gene of schizophrenia and a haplotype (CCACCAACT) significantly associated with schizophrenia is found.
Journal ArticleDOI
Rare mutations and hypermethylation of the ARC gene associated with schizophrenia
Yang-An Chuang,Tsung-Ming Hu,Chia-Hsiang Chen,Shih-Hsin Hsu,Hsin-Yao Tsai,Min-Chih Cheng,Min-Chih Cheng +6 more
TL;DR: The results suggest that both rare variants and epigenetic regulation of ARC contribute to the pathogenesis of schizophrenia in some patients.
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Differential Expression of Multiple Disease-Related Protein Groups Induced by Valproic Acid in Human SH-SY5Y Neuroblastoma Cells.
Tsung-Ming Hu,Tsung-Ming Hu,Hsiang-Sheng Chung,Lieh-Yung Ping,Shih-Hsin Hsu,Hsin-Yao Tsai,Shaw-Ji Chen,Shaw-Ji Chen,Min-Chih Cheng +8 more
TL;DR: The data indicate that VPA may modulate the differential expression of proteins involved in mitochondrial function and vitamin D receptor-mediated chromatin transcriptional regulation and proteins implicated in the pathogenesis of neurodegenerative diseases.
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Ultrarare Loss-of-Function Mutations in the Genes Encoding the Ionotropic Glutamate Receptors of Kainate Subtypes Associated with Schizophrenia Disrupt the Interaction with PSD95
TL;DR: The results suggest that the GRIK gene family harbors ultrarare LoF mutations in some patients with schizophrenia, and the identification of proteins that interact with the kainate receptors will be essential to determine kainates receptor-mediated signaling in the brain.
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Screening for Mutations in the TBX1 Gene on Chromosome 22q11.2 in Schizophrenia
TL;DR: The findings suggest that the TBX1 gene is unlikely a major susceptible gene for schizophrenia in an ethnic Chinese population for Taiwan, but a few rare mutations in the TBx1 gene may contribute to the pathogenesis of schizophrenia in some patients.