S
Shih-Hsin Hsu
Researcher at Taipei Veterans General Hospital
Publications - 21
Citations - 209
Shih-Hsin Hsu is an academic researcher from Taipei Veterans General Hospital. The author has contributed to research in topics: Gene & Single-nucleotide polymorphism. The author has an hindex of 8, co-authored 18 publications receiving 159 citations.
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Journal ArticleDOI
Role of the DLGAP2 gene encoding the SAP90/PSD-95-associated protein 2 in schizophrenia.
Jun-Ming Li,Chao-Lin Lu,Min-Chih Cheng,Sy-Ueng Luu,Shih-Hsin Hsu,Tsung-Ming Hu,Hsin-Yao Tsai,Chia-Hsiang Chen +7 more
TL;DR: The results indicate that DLGAP2 is a susceptible gene of schizophrenia and a haplotype (CCACCAACT) significantly associated with schizophrenia is found.
Journal ArticleDOI
Chronic methamphetamine treatment reduces the expression of synaptic plasticity genes and changes their DNA methylation status in the mouse brain.
TL;DR: The results show that chronic administration of Meth may lead to significant downregulation of the IEGs expression in both the frontal cortex and the hippocampus, which may partly account for the molecular mechanism of the action of METH.
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Genetic and functional analyses of early growth response (EGR) family genes in schizophrenia
Min-Chih Cheng,Yang-An Chuang,Chao-Lin Lu,Yu-Jung Chen,Sy-Ueng Luu,Jun-Ming Li,Shih-Hsin Hsu,Chia-Hsiang Chen,Chia-Hsiang Chen,Chia-Hsiang Chen +9 more
TL;DR: A tendency of gender-specific association of EGR2 and EGR4 in schizophrenia is suggested, with an elevated expression of E GR2 in lympoblastoid cell lines of female schizophrenia patients and a reduced E GR4 gene expression in male schizophrenia patients.
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Rare mutations and hypermethylation of the ARC gene associated with schizophrenia
Yang-An Chuang,Tsung-Ming Hu,Chia-Hsiang Chen,Shih-Hsin Hsu,Hsin-Yao Tsai,Min-Chih Cheng,Min-Chih Cheng +6 more
TL;DR: The results suggest that both rare variants and epigenetic regulation of ARC contribute to the pathogenesis of schizophrenia in some patients.
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Genetic analysis of the DLGAP1 gene as a candidate gene for schizophrenia.
Jun-Ming Li,Chao-Lin Lu,Min-Chih Cheng,Sy-Ueng Luu,Shih-Hsin Hsu,Chia-Hsiang Chen,Chia-Hsiang Chen,Chia-Hsiang Chen +7 more
TL;DR: Wang et al. as discussed by the authors identified six genetic variants, including five known SNPs (rs145691437, rs3786431, rs201567254, rs3745051 and rs11662259), and one rare missense mutation (c.1922A>G) in this sample.