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Chia-Hsiang Chen
Researcher at Chang Gung University
Publications - 106
Citations - 2908
Chia-Hsiang Chen is an academic researcher from Chang Gung University. The author has contributed to research in topics: Single-nucleotide polymorphism & Gene. The author has an hindex of 29, co-authored 106 publications receiving 2512 citations. Previous affiliations of Chia-Hsiang Chen include National Yang-Ming University & National Health Research Institutes.
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Journal ArticleDOI
Prevalence of autoimmune diseases in in-patients with schizophrenia: nationwide population-based study
Shaw Ji Chen,Yu Lin Chao,Chuan Yu Chen,Chia-Ming Chang,Erin Chia Hsuan Wu,Chi-Shin Wu,Hsueh Han Yeh,Chia-Hsiang Chen,Hui Ju Tsai,Hui Ju Tsai +9 more
TL;DR: Schizophrenia was associated with a greater variety of autoimmune diseases than was anticipated and Gender-specific variation was found for Sjögren syndrome, hereditary haemolytic anaemia, myasthenia gravis, polymyalgia rheumatica and dermatomyositis.
Journal ArticleDOI
Identification and functional characterization of rare mutations of the neuroligin-2 gene (NLGN2) associated with schizophrenia
Chicheng Sun,Min Chih Cheng,Rosie Qin,Ding-Lieh Liao,Tzu-Ting Chen,Farn Jong Koong,Gong Chen,Chia-Hsiang Chen,Chia-Hsiang Chen,Chia-Hsiang Chen +9 more
TL;DR: This study systemically sequenced all the exons and promoter region of neuroligin-2 (NLGN2) gene in a sample of schizophrenia patients and control subjects and suggested defects in GABAergic synapse formation in the brain may be an important contributing factor for the onset of schizophrenia.
Journal ArticleDOI
High-resolution copy number variation analysis of schizophrenia in Japan
Itaru Kushima,Branko Aleksic,Masahiro Nakatochi,Teppei Shimamura,Tomoko Shiino,Akira Yoshimi,Hiroki Kimura,Yuto Takasaki,Chaochen Wang,Jingrui Xing,Kanako Ishizuka,Tomoko Oya-Ito,Yukako Nakamura,Yuko Arioka,T Maeda,Maeri Yamamoto,Mami Yoshida,H Noma,Shuko Hamada,Maki Morikawa,Yota Uno,Takashi Okada,Tetsuya Iidaka,Shuji Iritani,Toshimichi Yamamoto,Mitsuhiro Miyashita,Akiko Kobori,Makoto Arai,Masanari Itokawa,M C Cheng,Y A Chuang,Chia-Hsiang Chen,Michio Suzuki,Tsutomu Takahashi,Ryota Hashimoto,Hidenaga Yamamori,Yuka Yasuda,Yuichiro Watanabe,Ayako Nunokawa,Toshiyuki Someya,Masashi Ikeda,Tomoko Toyota,Takeo Yoshikawa,Shusuke Numata,Tetsuro Ohmori,Shohko Kunimoto,Daisuke Mori,Nakao Iwata,Norio Ozaki +48 more
TL;DR: The study shows the high genetic heterogeneity of SCZ and its clinical features and raises the possibility that genomic instability is involved in its pathogenesis, which may be related to the increased burden of de novo CNVs and variable expressivity of CNVs.
the neuroligin-2 gene (NLGN2) associated with schizophrenia
Chicheng Sun,Min-Chih Cheng,Rosie Qin,Ding-Lieh Liao,Tzu-Ting Chen,Farn-Jong Koong,Gong Chen,Chia-Hsiang Chen +7 more
TL;DR: In this article, the authors systemically sequenced all the exons and promoter region of neuroligin-2 (NLGN2) gene in a sample of 584 schizophrenia patients and 549 control subjects from Taiwan.
Journal ArticleDOI
Increased brain amyloid deposition in patients with a lifetime history of major depression: evidenced on 18F-florbetapir (AV-45/Amyvid) positron emission tomography.
Kuan-Yi Wu,Ing-Tsung Hsiao,Ing-Tsung Hsiao,Cheng-Sheng Chen,Chia-Hsiang Chen,Chia-Ju Hsieh,Chia-Ju Hsieh,Yau-Yau Wai,Chee-Jen Chang,Chee-Jen Chang,Hsiao-Jung Tseng,Tzue-Chen Yen,Tzue-Chen Yen,Chia-Yih Liu,Kun-Ju Lin,Kun-Ju Lin +15 more
TL;DR: Increased 18F-florbetapir binding values were found in patients with late-life major depression relative to comparison subjects in specific brain regions, despite no differences in age, sex, education, Mini Mental Status Examination score, vascular risk factor score, homocysteine and ApoE ε4 genotype between the two groups.