H
Hsiu Mei Hsieh-Li
Researcher at National Taiwan Normal University
Publications - 80
Citations - 1991
Hsiu Mei Hsieh-Li is an academic researcher from National Taiwan Normal University. The author has contributed to research in topics: Neuroprotection & Spinocerebellar ataxia. The author has an hindex of 24, co-authored 72 publications receiving 1659 citations. Previous affiliations of Hsiu Mei Hsieh-Li include Taipei Medical University Hospital & Taipei Medical University.
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Journal ArticleDOI
Human Mesenchymal Stem Cells Prolong Survival and Ameliorate Motor Deficit through Trophic Support in Huntington's Disease Mouse Models
Yuan Ta Lin,Yuan Ta Lin,Yijuang Chern,Che Kun James Shen,Hsin Lan Wen,Ya Chin Chang,Hung Li,Hung Li,Tzu Hao Cheng,Hsiu Mei Hsieh-Li +9 more
TL;DR: The data suggest that hBM-MSCs have neural differentiation improvement potential, neurotrophic support capability and an anti-apoptotic effect, and may be a feasible candidate for HD therapy.
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Genetic testing in spinocerebellar ataxia in Taiwan: Expansions of trinucleotide repeats in SCA8 and SCA17 are associated with typical Parkinson's disease
Yih-Ru Wu,Hsuan-Yuan Lin,Chiung Mei Chen,Katrina Gwinn-Hardy,Long Sun Ro,Yi Ching Wang,S. H. Li,Ji-Chuu Hwang,Kang Fang,Hsiu Mei Hsieh-Li,Ming-Liang Li,L. C. Tung,Ming Tsan Su,Kwok Tung Lu,Guoy Jen Lee-Chen +14 more
TL;DR: In this paper, DNA tests in normal subjects and patients with ataxia and Parkinson's disease (PD) were carried out to assess the frequency of spinocerebellar Ataxia (SCA) and to document the distribution of SCA mutations underlying ethnic Chinese in Taiwan.
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Selective improvement of cognitive function in adult and aged APP/PS1 transgenic mice by continuous non-shock treadmill exercise
TL;DR: It is found that there may exist an age-related difference in the effect of continuous non-shock treadmill exercise training on AD, and the exercise program selectively improved the spatial learning and memory associated with an increase in both cholinergic neurons in the medial septum (MS)/vertical diagonal band (VDB) and serotonergic neuron in the raphe nucleus of aged APP/PS1 transgenic mice.
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Long-term social isolation exacerbates the impairment of spatial working memory in APP/PS1 transgenic mice.
TL;DR: The findings demonstrate the susceptibility of APP/PS1 transgenic adult male mice to environmental manipulation and show that social isolation has remarkable effects on the genetically determined AD-like symptoms.
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Stathmin, a microtubule-destabilizing protein, is dysregulated in spinal muscular atrophy
Hsin Lan Wen,Hsin Lan Wen,Yuan Ta Lin,Yuan Ta Lin,Chen Hung Ting,Sue Lin-Chao,Sue Lin-Chao,Hung Li,Hung Li,Hsiu Mei Hsieh-Li +9 more
TL;DR: In this article, a potential link between stathmin and microtubule defects in SMA was identified by screening Smn-knockdown NSC34 cells through proteomics analysis.