H
Huan-De Li
Researcher at Central South University
Publications - 97
Citations - 2525
Huan-De Li is an academic researcher from Central South University. The author has contributed to research in topics: High-performance liquid chromatography & Mass spectrometry. The author has an hindex of 29, co-authored 95 publications receiving 2154 citations.
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Journal ArticleDOI
Determination of dansylated monoamine and amino acid neurotransmitters and their metabolites in human plasma by liquid chromatography-electrospray ionization tandem mass spectrometry.
TL;DR: This novel LC-ESI/MS/MS approach is precise, highly sensitive, specific, and sufficiently simple and can provide an alternative method for the quantification of the NTs and their metabolites in human plasma.
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Simultaneous determination of clozapine, olanzapine, risperidone and quetiapine in plasma by high-performance liquid chromatography-electrospray ionization mass spectrometry.
Zhiling Zhou,Xin Li,Kun-Yan Li,Zhihong Xie,Ze-Neng Cheng,Wenxin Peng,Feng Wang,Rong-Hua Zhu,Huan-De Li +8 more
TL;DR: The method is accurate, sensitive and simple for routine therapeutic drug monitoring (TDM) and for the study of the pharmacokinetics of the four drugs.
Journal ArticleDOI
Salvianolic acid B protects against lipopolysaccharide-induced behavioral deficits and neuroinflammatory response: involvement of autophagy and NLRP3 inflammasome.
Pei Jiang,Yujin Guo,Ruili Dang,Mengqi Yang,Dehua Liao,Huan-De Li,Zhen Sun,Qingyan Feng,Pengfei Xu +8 more
TL;DR: In this paper, the effects of prolonged lipopolysaccharide (LPS) treatment and SalB administration on behavioral changes, neuroinflammation, autophagic markers and NLRP3 activation in rat hippocampus were determined by using behavioral tests, real-time PCR analysis, western blot, and immunostaining.
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Metabolomic Analysis of Biochemical Changes in the Plasma and Urine of First-Episode Neuroleptic-Naïve Schizophrenia Patients after Treatment with Risperidone
Hua-Lin Cai,Huan-De Li,Xianzhong Yan,Bo Sun,Qi Zhang,Miao Yan,Wen-Yuan Zhang,Pei Jiang,Rong-Hua Zhu,Yi-Ping Liu,Ping-Fei Fang,Ping Xu,Hai-Yan Yuan,Xiang-Hui Zhang,Li Hu,Wen Yang,Hai-Sen Ye +16 more
TL;DR: Metabolic signatures consisting of monoamine and amino acid neurotransmitter (NT) metabolites in plasma/urine simultaneously between first-episode neuroleptic-naïve schizophrenia patients (FENNS) and healthy controls before and after a 6-week risperidone monotherapy suggest that the patient NT profiles are restoring during treatment.
Journal ArticleDOI
Neurochemical effects of chronic administration of calcitriol in rats.
Pei Jiang,Li-Hong Zhang,Hua-Lin Cai,Huan-De Li,Yi-Ping Liu,Mimi Tang,Ruili Dang,Wen-Ye Zhu,Ying Xue,Xin He +9 more
TL;DR: The effects of calcitriol in the major neurotransmitter systems are shown, providing new evidence for the role of VD in brain function.