Showing papers in "Journal of Chromatography B in 2004"

TL;DR: Several novel chemometric methods for evaluating the fingerprints of herbal products, such as the method based on information theory, similarity estimation, chemical pattern recognition, spectral correlative chromatogram (SCC), multivariate resolution, etc, are discussed in detail with examples, which showed that the combination of chromatographic fingerprints and the chemometric evaluation might be a powerful tool for quality control of herbal medicines.

TL;DR: This short review aims to present, in clear English, a summary of the principal synthetic considerations pertaining to good practice in the polymerisation aspects of molecular imprinting, and is primarily aimed at researchers familiar with molecular imprinted methods but with little or no prior experience in polymer synthesis.

TL;DR: The results show that GC-MS and SPME with on-fiber derivatization is a simple, rapid and sensitive and solvent-free method for determination of low concentration acetone in breath and analysis of breath acetone can be used as supplementary tool for diagnosis of diabetes.

TL;DR: The present review focuses on the antioxidant activity, chemical types, sampling and sample processing procedures, and separation using various chromatographic and electrophoretic techniques.

TL;DR: This review seeks to highlight the more remarkable advantages of the imprinting technique in the development of new efficient DDS as well as pointing out some possibilities to adapt the synthesis procedures to create systems compatible with both the relative instable drug molecules and the sensitive physiological tissues with which MIP-based DDS would enter into contact when administered.

TL;DR: It is proposed that the potential trend in the application of ATPS processes will involve the recovery of high-value bio-particulate products with medical applications, which will address the urgent need to rapidly and economically bring new biopharmaceutical products to market using scaleable and efficient bioprocess technology.

TL;DR: A new technique for sample preparation on-line with LC and GC-MS assays was developed and validated and the standard curves were evaluated by the means of quadratic regression and weighted by inverse of the concentration.

TL;DR: The molecular diversity of different marine peptides is described as well as information about their biological properties and mechanisms of action is provided.

TL;DR: This review presents an overview on the promising field of molecularly imprinted membranes (MIM), focusing on the separation of molecules in liquid mixtures via membrane transport selectivity.

TL;DR: A review of methods that take into account binding site heterogeneity when calculating the binding properties of MIPs, including the bi-Langmuir, Freundlich, and Langmuir-Freundlich binding models.

TL;DR: New techniques such as near infrared spectroscopy (NIRS) and enzyme immunosassay (EIA) recently used for the determination of ginsenosides will be discussed.

TL;DR: Applications of special extraction sorbents, such as restricted access media (RAM) and large particle supports (LPS), allowing the direct and repetitive injection of complex biological matrices, lead to the automation, simplification and speeding up of the sample preparation process.

TL;DR: By comparison of volatiles in breath and in blood, it is demonstrated that hexanal and heptanal in breath were originated from blood and screening of lung cancer by breath analysis be feasible.

TL;DR: It is suggested that a subset of the urinary nucleosides identified with metabonomics correlate better with cancer diagnosis than the traditional single tumor marker alpha-fetoprotein (AFP).

TL;DR: Applications of both chromatographic and electrophoretic techniques to the analysis of medicinal plants and Chinese traditional medicine preparations over the last 3 years are outlined in this review.

TL;DR: The literature data on levels of norharman and harman in fried meat and fish, meat extracts, alcoholic drinks, and coffee brews is summarized to indicate that inhalative exposure leads to a rapid increase in plasma levels and high bioavailability of norHarman and Harman and there are indications that sublingual absorption may increase dietary uptake of beta-carbolines.

TL;DR: The focus of this review paper is on the analytical methodologies, which included the combination of sample preparation tools and chromatographic techniques for the chemical standardization of marker compounds or active ingredients in botanicals and herbal preparations.

TL;DR: A sensitive method for measuring 13 phthalate metabolites in breast milk using automated solid phase extraction (SPE) coupled to isotope dilution-high-performance liquid chromatography (HPLC)-negative ion electrospray ionization-tandem mass spectrometry shows good reproducibility and accuracy and accuracy.

TL;DR: The modified method permitted for the first time, the separation and quantification of mono-n-butyl phthalate (mBP) and its structural isomer miBP, and resulted in an increased sample throughput, lower solvent use, and better reproducibility than the manual SPE.

TL;DR: Supermacroporous monolithic acrylamide (AAm)-based cryogels were prepared by radical cryo-polymerizaton (polymerization in the moderately frozen system) of AAm with functional monomers and cross-linker N,N'-methylene-bis-acrylamides with pore size of 5-100 microm and total protein binding capacity was independent of the flow rates.

TL;DR: In this article, the authors provide an overview of various separation, detection, and identification techniques employed for the quantitative and qualitative determination of Scutellaria baicalensis Georgi's main active components.

TL;DR: A review is presented on the CE analysis of colloidal/nano particles and several of the encountered difficulties in analysis are presented as well as the methods employed to overcome them.

TL;DR: The chromatographic techniques applied for the determination, separation and identification of chemical compounds of H. rhamnoides L. are reviewed and biological properties of the plant and its pharmacological effects and use in traditional medicine have also been reviewed.

TL;DR: Data show a general trend towards a reduction of HA formation both in model systems and in real foods as well as an effective modulation of biotransformation and metabolism.

TL;DR: The present review summarizes the various chromatographic and electrophoretic methods (as well as sample pretreatment methods) typically employed to achieve such extraction/separation procedures of Lingzhi.

TL;DR: Findings provide evidence that under the employed experimental conditions specific analyte binding to imprinted binding sites plays a minor role in selective OTA retention and problems inherent to MIP-based solid-phase extraction have been addressed.

TL;DR: A new method, based on stir bar sorptive extraction (SBSE) with in situ derivatization and thermal desorption (TD)-gas chromatography-mass spectrometry (GC-MS) is described for the determination of trace amounts of bisphenol A (BPA) in river water, urine, plasma, and saliva samples.

TL;DR: RP-HPLC is not a commonly used chromatographic method to assess purity of monoclonal antibodies but unlike to SEC and SDS-PAGE, was able to show and to quantify the family of structures present in 7H2HM, which were also identified by peptide mapping, mass spectrometry and microsequencing.

TL;DR: Results from the preliminary clinical study demonstrate significant penetration of all sunscreen agents into the skin, and oxybenzone and metabolites across the skin.

TL;DR: A method for performing discovery stage pharmacokinetic analysis using whole blood dried onto filter paper is described, and its application to early screening of drug candidates proves to be robust, reliable and reproducible.