H
Huanwen Chen
Researcher at Purdue University
Publications - 11
Citations - 1722
Huanwen Chen is an academic researcher from Purdue University. The author has contributed to research in topics: Mass spectrometry & Extractive electrospray ionization. The author has an hindex of 11, co-authored 11 publications receiving 1648 citations.
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Extractive electrospray ionization for direct analysis of undiluted urine, milk and other complex mixtures without sample preparation.
TL;DR: On-line droplet-droplet extraction occurs when a sample spray intersects a reagent electrospray; this allows continuous analysis of trace amounts of compounds directly in complex matrices including undiluted urine, milk and polluted water over extended periods of time.
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Direct, trace level detection of explosives on ambient surfaces by desorption electrospray ionization mass spectrometry
TL;DR: Desorption electrospray ionization (DESI) mass spectrometry is used to detect trace amounts of explosives present on a variety of ambient surfaces in 5-second analysis times without any sample preparation.
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Desorption Electrospray Ionization Mass Spectrometry for High-Throughput Analysis of Pharmaceutical Samples in the Ambient Environment
TL;DR: Positive and negative ion DESI are used to characterize the active ingredients in pharmaceutical samples formulated as tablets, ointments, and liquids, and carryover effects are minimized in high-throughput on-line analysis of pharmaceutical samples.
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Principal component analysis of urine metabolites detected by NMR and DESI-MS in patients with inborn errors of metabolism
Zhengzheng Pan,Haiwei Gu,Nari Talaty,Huanwen Chen,Narasimhamurthy Shanaiah,Bryan E. Hainline,R. Graham Cooks,Daniel Raftery +7 more
TL;DR: The combined approach discussed here may prove useful in the rapid screening of biological fluids from sick patients and may help to improve the understanding of these rare diseases.
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Combining desorption electrospray ionization mass spectrometry and nuclear magnetic resonance for differential metabolomics without sample preparation
TL;DR: Principal component analysis (PCA) is used to shortlist compounds with potential for biomarker screening which are responsible for significant differences between control urine samples and samples from diseased animals.