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Huiqin Pan

Researcher at Chinese Academy of Sciences

Publications -  21
Citations -  652

Huiqin Pan is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Uncaria & Panax notoginseng. The author has an hindex of 13, co-authored 19 publications receiving 474 citations.

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An enhanced targeted identification strategy for the selective identification of flavonoid O-glycosides from Carthamus tinctorius by integrating offline two-dimensional liquid chromatography/linear ion-trap-Orbitrap mass spectrometry, high-resolution diagnostic product ions/neutral loss filtering and liquid chromatography-solid phase extraction-nuclear magnetic resonance

TL;DR: An enhanced targeted identification strategy is presented and validated by the selective identification of flavonoid O-glycosides (FOGs) from Carthamus tinctorius and can improve the potency, efficiency, and accuracy in the detection of new compounds from medicinal herbs and other natural sources.
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Global profiling combined with predicted metabolites screening for discovery of natural compounds: Characterization of ginsenosides in the leaves of Panax notoginseng as a case study.

TL;DR: Two methods were adopted to improve the performance of liquid chromatography-mass spectrometry, including offline two-dimensional LC to extend the peak capacities and predicted metabolites screening (PMS) to automatically screen the targets with expanded databases.
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An integrated strategy for the systematic characterization and discovery of new indole alkaloids from Uncaria rhynchophylla by UHPLC/DAD/LTQ-Orbitrap-MS

TL;DR: This study presents an integrated strategy that uses ultrahigh-performance liquid chromatography/linear ion-trap quadrupole/Orbitrap mass spectrometry coupled with in-house library data for the systematic characterization and discovery of new potentially bioactive molecules from indole alkaloids.
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Mass defect filtering-oriented classification and precursor ions list-triggered high-resolution mass spectrometry analysis for the discovery of indole alkaloids from Uncaria sinensis.

TL;DR: A practical chemical dereplication strategy that can enhance the efficiency and has the potential to be a routine approach for the discovery of new natural compounds is reported.