H
Hyangyee Oh
Researcher at Howard Hughes Medical Institute
Publications - 17
Citations - 1801
Hyangyee Oh is an academic researcher from Howard Hughes Medical Institute. The author has contributed to research in topics: Dosage compensation & MSL complex. The author has an hindex of 15, co-authored 17 publications receiving 1692 citations. Previous affiliations of Hyangyee Oh include Harvard University & Baylor College of Medicine.
Papers
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Journal ArticleDOI
In vivo regulation of Yorkie phosphorylation and localization.
Hyangyee Oh,Kenneth D. Irvine +1 more
TL;DR: In this paper, the Warts kinase has been shown to promote the activation of Yki at multiple sites, including serine 168, which is a critical site through which negative regulation by Warts-mediated phosphorylation occurs.
Journal ArticleDOI
In vivo analysis of Yorkie phosphorylation sites.
Hyangyee Oh,Kenneth D. Irvine +1 more
TL;DR: Investigation of the role of Yki and its mammalian homolog Yes-associated protein (YAP) in development and oncogenesis should include evaluations of additional sites of phosphorylation by Wts, suggesting that there are additional mechanisms for regulating Yki/YAP activity.
Journal ArticleDOI
Cooperative regulation of growth by Yorkie and Mad through bantam.
Hyangyee Oh,Kenneth D. Irvine +1 more
TL;DR: The results indicate that in promoting the growth of Drosophila tissues, Fat-Hippo and Dpp signaling contribute distinct subunits of a shared transcriptional activation complex, Yorkie:Mad.
Journal ArticleDOI
Zyxin links fat signaling to the hippo pathway.
TL;DR: Using genetic and molecular analyses, the authors identify Zyx as a positive regulator of Hippo signaling and characterize its role within the pathway.
Journal ArticleDOI
Yorkie: the final destination of Hippo signaling
Hyangyee Oh,Kenneth D. Irvine +1 more
TL;DR: In the 5 years since the first report linking Yorkie to Hippo signaling, intense interest in this pathway has led to rapid increases in understanding of the action and regulation of Yorkie/Yap, which are reviewed here.