H
Hyounju Kim
Researcher at Josai University
Publications - 22
Citations - 1171
Hyounju Kim is an academic researcher from Josai University. The author has contributed to research in topics: Fish oil & Insulin resistance. The author has an hindex of 12, co-authored 22 publications receiving 1113 citations.
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Journal ArticleDOI
Conjugated linoleic acid supplementation reduces adipose tissue by apoptosis and develops lipodystrophy in mice.
Nobuyo Tsuboyama-Kasaoka,Mayumi Takahashi,Kentaro Tanemura,Hyounju Kim,Tsuyoshi Tange,Hitoshi Okuyama,Masaaki Kasai,Shinji Ikemoto,Osamu Ezaki +8 more
TL;DR: It is demonstrated that intake of CLA reduces adipose tissue by apoptosis and results in lipodystrophy, but hyperinsulinemia by CLA can be normalized by leptin administration.
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Up-regulation of liver uncoupling protein-2 mRNA by either fish oil feeding or fibrate administration in mice
TL;DR: Fish oil feeding and fibrate administration each up-regulated UCP2 mRNA expression in liver possibly via PPARalpha and hence each has the potential of increasing energy expenditure for prevention of obesity.
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Up-Regulation of Uncoupling Protein 3 (UCP3) mRNA by Exercise Training and Down-Regulation of UCP3 by Denervation in Skeletal Muscles
Nobuyo Tsuboyama-Kasaoka,Nobuyo Tsunoda,Kayo Maruyama,Mayumi Takahashi,Hyounju Kim,Shinji Ikemoto,Osamu Ezaki +6 more
TL;DR: The data indicate that UCP3 may have a role for fine adjustments of energy expenditure and that up-regulation of U CP3 mRNA may be a defense mechanism against extra energy supply to consume extra energy in skeletal muscles.
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Anti-obesity effect of fish oil and fish oil-fenofibrate combination in female KK mice
TL;DR: Fish oil inhibited body weight gain and exhibited an anti-obesity effect through the inhibition of lipid synthesis in female KK mice, as well as the hepatic mRNA expression of lipogenic and lipidolytic genes.
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Overexpression of GLUT4 in mice causes up-regulation of UCP3 mRNA in skeletal muscle.
Nobuyo Tsuboyama-Kasaoka,Nobuyo Tsunoda,Kayo Maruyama,Mayumi Takahashi,Hyounju Kim,David W. Cooke,M. Daniel Lane,Osamu Ezaki +7 more
TL;DR: Findings indicate that overexpression of GLUT4 up-regulates UCP3 expression in skeletal muscle and down-regulate UCP1 expression in BAT, possibly by increasing the rate of glucose uptake into these tissues.