H
Hyun-Na Koo
Researcher at Wonkwang University
Publications - 16
Citations - 369
Hyun-Na Koo is an academic researcher from Wonkwang University. The author has contributed to research in topics: Apoptosis & Fragmentation (cell biology). The author has an hindex of 7, co-authored 16 publications receiving 346 citations.
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Journal ArticleDOI
INHIBITION OF TNF-α AND IL-6 PRODUCTION BY AUCUBIN THROUGH BLOCKADE OF NF-κB ACTIVATION IN RBL-2H3 MAST CELLS
Hyun-Ja Jeong,Hyun-Na Koo,Ho-Jeong Na,Mi-Sun Kim,Seung-Heon Hong,Jung-Woo Eom,Kyung-Suk Kim,Tae-Yong Shin,Hyung-Min Kim +8 more
TL;DR: Results suggest that aucubin is a specific inhibitor of NF-κB activation in mast cells, which might explain its beneficial effect in the treatment of chronic allergic inflammatory diseases.
Journal ArticleDOI
Taraxacum officinale protects against cholecystokinin-induced acute pancreatitis in rats.
Sang-Wan Seo,Hyun-Na Koo,Hyo-Jin An,Kang-Beom Kwon,Byung-Cheal Lim,Eun-A Seo,Do-Gon Ryu,Goo Moon,Hong-Yeoul Kim,Hyung-Min Kim,Seung-Heon Hong +10 more
TL;DR: To may have a protective effect against CCK octapeptide-induced acute pancreatitis, and increased the pancreatic levels of HSP60 and HSP72, and the secretion of pro-inflammatory cytokines.
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Nitric oxide production by high molecular weight water-soluble chitosan via nuclear factor-κB activation
Hyun-Ja Jeong,Hyun-Na Koo,Eun-Young Oh,Han-Jung Chae,Hyung-Ryong Kim,Sang-Bong Suh,Cheorl-Ho Kim,Kwang Ho Cho,Byung Rim Park,Seung-Taeck Park,Young-Mi Lee,Hyung-Min Kim +11 more
TL;DR: The present results indicate that the capacity of W SC to increase NO production from rIFN-γ-primed RAW 264.7 macrophages is the result of WSC-induced TNF-α secretion via the signal transduction pathway of NF-κB activation.
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INHIBITORY EFFECT OF ARTEMISIA CAPILLARIS ON ETHANOL-INDUCED CYTOKINES (TNF-α, IL-1α) SECRETION IN HEP G2 CELLS
Hyun-Na Koo,Seung-Heon Hong,Hyun-Ja Jeong,Eun-Hee Lee,Nam-Guek Kim,Su-Deock Choi,Ki-Woong Ra,Kang-San Kim,Byung-Ki Kang,Jeong-Joong Kim,Jeong Guk Oh,Hyung-Min Kim +11 more
TL;DR: It is suggested that an aqueous extract of Artemisia capillaris THUNB (Compositae) plant (AC) may prevent the EtOH-induced cytotoxicity through inhibition of the apoptosis of Hep G2 cells.
Journal ArticleDOI
Inhibitory effects of mast cell-mediated allergic reactions by cell cultured Siberian Ginseng.
Hyunjo Jeong,Hyun-Na Koo,Noh-Yil Myung,Min-Kyo Shin,Jeong-Joong Kim,Dae-Ki Kim,Kyoung-Soo Kim,Hyun-A Kim,Yun Mi Lee +8 more
TL;DR: The studies provide evidence that SG may be beneficial in the treatment of various types of allergic diseases and dose-dependently inhibited compound 48/80-induced systemic allergy.